130198-05-9 Usage
Description
1-[2-Amino-1-(4-methoxyphenyl)-ethyl]-cyclohexanol hydrochloride, also known as Venlafaxine EP Impurity C, is a chemical compound derived from the modification of the antidepressant drug venlafaxine. It is characterized by the presence of an amino group, a cyclohexanol ring, and a 4-methoxyphenylethyl moiety, which contribute to its unique chemical properties and potential applications.
Uses
Used in Pharmaceutical Industry:
1-[2-Amino-1-(4-methoxyphenyl)-ethyl]-cyclohexanol hydrochloride is used as an active pharmaceutical ingredient for the development of antidepressant medications. It exhibits anti-depressant activity in mice, making it a promising candidate for further research and development in the treatment of depression and related mood disorders.
Used in Research and Development:
1-[2-Amino-1-(4-methoxyphenyl)-ethyl]-cyclohexanol hydrochloride is used as a research compound for studying the mechanisms of action and potential side effects of antidepressant drugs. Its unique structure allows scientists to investigate the relationship between chemical composition and therapeutic efficacy, ultimately contributing to the advancement of novel and more effective treatments for depression and other mental health conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 130198-05-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,0,1,9 and 8 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 130198-05:
(8*1)+(7*3)+(6*0)+(5*1)+(4*9)+(3*8)+(2*0)+(1*5)=99
99 % 10 = 9
So 130198-05-9 is a valid CAS Registry Number.
130198-05-9Relevant articles and documents
Preparation method of venlafaxine hydrochloride intermediate
-
Paragraph 0032-0067, (2021/01/11)
The invention belongs to the technical field of organic synthesis, and relates to a preparation method of a venlafaxine hydrochloride intermediate, which comprises the following steps: heating, quenching, extracting, concentrating and salifying. A venlafaxine impurity C synthesized by the method is high in yield, good in purity, safe in reaction, simple to operate, free of special requirements onequipment and suitable for industrial production.
DERIVATIVES OF (-)-VENLAFAXINE AND METHODS OF PREPARING AND USING THE SAME
-
, (2015/11/23)
Methods of preparing, and compositions comprising, derivatives of (?)-venlafaxine are disclosed. Also disclosed are methods of treating and preventing diseases and disorders including, but not limited to, affective disorders such as depression, bipolar and manic disorders, attention deficit disorder, attention deficit disorder with hyperactivity, Parkinson's disease, epilepsy, cerebral function disorders, obesity and weight gain, incontinence, dementia and related disorders.
PROCESS FOR PREPARATION OF 0-DESMETHYLVENLAFAXINE AND ITS ANALOGUES
-
Page/Page column 12, (2008/06/13)
The present invention belongs to the field of organic chemistry and refers to a process for the preparation of O-desmethylvenlafaxine (l-[2-Dimethylamino)-l-(4-hydroxyphenyl)ethyl]cyclo- hexanol), its analogues and pharmaceutical acceptable salts thereof. The invention also relates to a catalytic hydrogenation of cyano-group of the substituted acetonitrile.