130252-11-8

Basic information

• Product Name: Cyclohexyl-6 cyano-1 cyclohexene
• Synonyms: Cyclohexyl-6 cyano-1 cyclohexene
• CAS NO: 130252-11-8
• Molecular Weight: 189.301
• Mol File: 130252-11-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Cyclohexyl-6 cyano-1 cyclohexene(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexyl-6 cyano-1 cyclohexene(130252-11-8)
• EPA Substance Registry System: Cyclohexyl-6 cyano-1 cyclohexene(130252-11-8)

Safety Data

• Hazardous Substances Data: 130252-11-8(Hazardous Substances Data)

Upstream product

• 130251-99-9 6-acetoxy-1-cyclohexene-1-carbonitrile 
• 931-50-0 cyclohexylmagnesium bromide 

Relevant articles and documents

SUBSTITUTION NUCLEOPHILE D'ACETATES DE CYCLENOLS ALLYLIQUES FONCTIONNELS PAR DES ORGANOMETALLIQUES EN PRESENCE DE SELS CUIVREUX. APPLICATION A UNE SYNTHESE RAPIDE DE LA (+/-) MITSUGASHIWALACTONE

Substitution of functional allylic cycloalkenol acetates by Grignard reagents (primary, secondary, tertiary-alkyl, vinyl, aryl) in the presence of a catalytic amount (2.5percent equivalent) of cuprous iodide at low temperature, gives high yields of various functional α-substituted cycloalkenes.The reaction can be applied to lithium enolates of esters and need no catalyst, but may be performed with HMPA as cosolvent.It is illustrated by a short (6 steps) and efficient total selective synthesis of (+/-)-mitsugashiwalactone from 2,5-dimethoxytetrahydrofuran with 33percent overall yield.