1303-33-9 Usage
Description
Arsenic (III) Sulfide, also known as Arsenic Sesquisulfide or Arsenic Trisulfide, is a yellow or orange crystalline solid or powder with a red allotrope modification. It has a density of 3.46 g/cm3, melts at 310°C, and boils at 707°C. Arsenic (III) Sulfide is insoluble in water but soluble in liquid ammonia and alkalies. It is combustible and toxic by inhalation (dust) and ingestion. It occurs naturally as the mineral orpiment and has been used for various applications throughout history.
Uses
1. Medical Applications:
Used in the treatment of acute promyelocytic leukemia.
2. Semiconductor and Photoconductor Industry:
Arsenic (III) Sulfide is used as an inorganic photoresist in the fabrication of photonic crystals and 3-D nanostructures.
It is also used in the manufacture of electrical semiconductors and photoconductors.
3. Acousto-Optic Material:
Arsenic (III) Sulfide is used as an acousto-optic material.
4. Pigment and Tanning Agent:
It is used as a pigment in various industries.
Arsenic (III) Sulfide is also used as a tanning agent.
5. Infrared Optics:
It is used in the manufacture of chalcogenide glass for infrared optics.
Arsenic (III) Sulfide is also used in the production of infrared-transmitting glass.
6. Analytical Testing:
Arsenic (III) Sulfide is used as an analytical test for the presence of dissimilatory arsenic-reducing bacteria (DARB).
7. Manufacturing Applications:
It is used in the manufacture of glass, particularly infrared-transmitting glass.
Arsenic (III) Sulfide is also used in the production of oil cloth and linoleum.
8. Depilating Agent:
Arsenic (III) Sulfide is used for depilating hides.
9. Pyrotechnics:
It is used in the pyrotechnics industry.
10. Historical Industrial Uses:
As2S3 (orpiment) and As2S2 (realgar) have been used as early as 2000 BC as drugs to cure cancerous tumors, ulcers, and other diseases of the time.
Later, Galen (130-200 AD) recommended the application of a paste of arsenic sulfide against ulcers.
Preparation
Arsenic sesquioxide may be prepared by heating arsenic trioxide with hydrogen sulfide:As2O3 + 3 H2S → As2S3 + 3 H2OAlternatively, it may be precipitated out from a solution of arsenous acid or arsenic trioxide in dilute hydrochloric acid by passing hydrogen sulfide into the solution:2H3AsO3 + 3H2S → As2S3 + 6H2O.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
ARSENIC (III) SULFIDE is dissolved by alkalis and by hydrochloric acid (slowly). Decomposed by nitric acid. May react with oxidizing agents to generate heat and products that may be flammable, combustible, or otherwise reactive. The reactions may be violent. ARSENIC (III) SULFIDE reacts with concentrated solutions of chloric acid with incandescence [Mellor Supp. II Part I:584 1956]. Generates toxic gaseous hydrogen sulfide on contact with acids.
Health Hazard
(Acute and sub-acute poisoning are not common.) Repeated inhalation causes irritation of nose, laryngitis, mild bronchitis. Ingestion causes weakness, loss of appetite, gastrointestinal disturbances, peripheral neuritis, occasional hepatitis. Contact with eyes causes irritation. Irritates skin, especially where moist; if not treated, may cause ulceration.
Fire Hazard
Combustible material: may burn but does not ignite readily. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.
Safety Profile
Confirmed human
carcinogen with experimental tumorigenic
data. A poison. Reacts violently with H202,
(m03 + S). When heated to
decomposition or on contact with acid or
acid fumes it emits highly toxic fumes of
S02, H2S, and As. Reacts with water or
steam to emit toxic and flammable vapors.
Potential Exposure
Arsenic trisulfide is used in the manufacture
of glass, oil cloth, linoleum, electrical semiconductors,
fireworks and used as a pigment.
Shipping
UN1557 Arsenic compounds, solid, n.o.s. inorganic,
including arsenates, n.o.s.; arsenites, n.o.s.; arsenic
sulfides, n.o.s.; and organic compounds of arsenic, n.o.s.,
Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
Incompatibilities
A strong reducing agent; avoid contact
with oxidizers (such as perchlorates, peroxides, permanganates,
chlorates, and nitrates) and potassium nitrate mixed
with sulfur, since violent reactions occur. Water contact
forms hydrogen sulfide. Incompatible with acids, halogens.
Contact with acids or acid mists releases deadly arsine gas.
Waste Disposal
Consult with environmental
regulatory agencies for guidance on acceptable disposal
practices. Generators of waste containing this contaminant
(≥100 kg/mo) must conform with EPA regulations governing
storage, transportation, treatment, and waste disposal.
Check Digit Verification of cas no
The CAS Registry Mumber 1303-33-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,3,0 and 3 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1303-33:
(6*1)+(5*3)+(4*0)+(3*3)+(2*3)+(1*3)=39
39 % 10 = 9
So 1303-33-9 is a valid CAS Registry Number.
InChI:InChI=1/As4S6/c5-1-6-3-8-2(5)9-4(7-1)10-3
