130318-01-3Relevant articles and documents
Synthesis of polysubstituted pyridines from oxime acetates using NH4I as a dual-function promoter
Xia, Yujia,Cai, Jinhui,Huang, Huawen,Deng, Guo-Jun
, p. 124 - 129 (2017/12/27)
Pyridine formation with oxime acetates as the building blocks under metal-free conditions is described. Ammonium iodide has proved to be a highly efficient promoter for oxime N-O bond reduction and subsequent condensation reactions, whereby it played a dual-function role in the transformation. While the three-component reaction of oxime acetates, benzaldehydes, and 1,3-dicarbonyls proceeded well with the assistance of a stoichiometric amount of ammonium iodide, the condensation of oximes and acroleins was enabled by using a catalytic initiator to afford substituted pyridines. By this protocol, substituted pyridine products were generated in moderate to excellent yields with tolerance towards a broad range of functional groups.
Palladium-catalyzed multi-component synthesis of steroidal A- and D-ring fused 5,6-disubstituted pyridines under microwave irradiation
Shekarrao, Kommuri,Nath, Dipankar,Kaishap, Partha Pratim,Gogoi, Sanjib,Boruah, Romesh C.
, p. 1126 - 1133 (2013/10/08)
The preparation of steroidal A-, D-ring fused 5,6-disubstituted pyridines and nonsteroidal substituted pyridines is described form Pd(OAc)2 catalyzed multi-component reaction of steroidal/nonsteroidal β-halovinyl aldehyde, alkyne and benzylamin
Highly efficient synthesis of isoquinolines via nickel-catalyzed annulation of 2-iodobenzaldimines with alkynes: Evidence for dual pathways of alkyne insertion
Korivi, Rajendra Prasad,Cheng, Chien-Hong
, p. 5179 - 5182 (2007/10/03)
(Chemical Equation Presented) A wide range of substituted isoquinolines were synthesized via a highly efficient nickel-catalyzed annulation of the tert-butyl imines of 2-iodobenzaldehydes and various alkynes; examination of the regiochemistry of isoquinol