13035-19-3 Usage
Description
4-Aminopiperidine is an organic compound that serves as a crucial building block in the synthesis of various pharmaceuticals and bioactive molecules. It is a heterocyclic amine with a nitrogen atom in the ring structure, which contributes to its reactivity and versatility in chemical reactions.
Uses
Used in Pharmaceutical Industry:
4-Aminopiperidine is used as a reactant for the synthesis of various pharmaceutical compounds, including:
1. Cdk5/p25 kinase inhibitors for the treatment of neurodegenerative diseases.
2. Antimalarials to combat malaria, a life-threatening disease caused by parasites.
3. Selective cyclin-dependent kinase 4/6 inhibitors, which have potential applications in cancer therapy.
4. IKKβ inhibitors, which can be used to modulate the immune response and treat inflammatory conditions.
5. Orally bioavailable P2Y12 antagonists for the inhibition of platelet aggregation, useful in the prevention and treatment of cardiovascular diseases.
6. Human and murine soluble epoxide hydrolase inhibitors, which may have implications in the treatment of hypertension and other related conditions.
These applications highlight the importance of 4-Aminopiperidine as a versatile and valuable compound in the development of new drugs and therapies across different medical fields.
Check Digit Verification of cas no
The CAS Registry Mumber 13035-19-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,0,3 and 5 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 13035-19:
(7*1)+(6*3)+(5*0)+(4*3)+(3*5)+(2*1)+(1*9)=63
63 % 10 = 3
So 13035-19-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H12N2/c6-5-1-3-7-4-2-5/h5,7H,1-4,6H2
13035-19-3Relevant articles and documents
USE OF INTERMEDIATES ((R ) -2,2, 4-TRIMETHYL-L, 3-DIOXOLANE-4-YL) METHANOL (A), 3-F LUORO-4-NITRO-PHENOL (B) AND 1- (4-CHLORO- BENZYL) -PIPERIDIN-4-YLAMINE (C)
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Page/Page column 11; 23, (2009/04/25)
The present invention relates to novel processes for the preparation of intermediate compounds which can be used to prepare therapeutic agents. The present invention also relates to novel intermediate compounds which can be used to prepare therapeutic agents. More specifically, the invention relates to the use of intermediates ((R) -2,2,4-trimethyl-l, 3- dioxolane-4 -yl) methanol (A), 3-f luoro-4-nitro-phenol (B) and 1- (4-chloro-benZyl) -piperidin-4-ylamine (C).
Indazole derivatives having monocyclic amine
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, (2008/06/13)
An indazole compound having the formula (I): wherein: R1 is hydrogen, C1 -C6 alkyl, C3 -C6 alkenyl or C3 -C6 cycloalkyl; Q is carbonyl, thiocarbonyl or methylene; and R2 is a group of the formula (II) or (IV); STR1 wherein R1 is C1 -C6 alkyl, C3 -C6 alkenyl or benzyl, of which a phenyl group thereof is optionally mono- or di-substituted by the same or different halogen or methoxy; m is 0 to 2; n and o is 1 or 2. The compound exhibits 5-HT4 receptor agonist activity.