13036-87-8

Basic information

• Product Name: ethylcarbamodithioic acid
• CAS NO: 13036-87-8
• Molecular Formula: C₃H₆NS₂*Na
• Molecular Weight: 121.2244
• Mol File: 13036-87-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 144.3°C at 760 mmHg
• Flash Point: 41.1°C
• Density: 1.144g/cm³
• Vapor Pressure: 5.13mmHg at 25°C
• Refractive Index: 1.569
• CAS DataBase Reference: ethylcarbamodithioic acid(CAS DataBase Reference)
• NIST Chemistry Reference: ethylcarbamodithioic acid(13036-87-8)
• EPA Substance Registry System: ethylcarbamodithioic acid(13036-87-8)

Safety Data

• Hazardous Substances Data: 13036-87-8(Hazardous Substances Data)

Upstream product

• 75-15-0 carbon disulfide 
• 75-04-7 ethylamine 

Downstream Products

• 7629-48-3 N-Ethyl-S-thiocarbamylthio-hydracylsaeure 
• 121215-97-2 3-Ethyl-6-(4-methoxy-phenyl)-2-thioxo-[1,3]thiazinan-4-one 
• 13037-14-4 ethyl-dithiocarbamic acid methyl ester 
• 121216-03-3 3-Ethyl-6-(4-nitro-phenyl)-2-thioxo-[1,3]thiazinan-4-one 
• 7629-40-5 3-Ethyl-2-thioxotetrahydro-1,3-thiazin-4-on 
• 542-85-8 Ethyl isothiocyanate 
• 636-04-4 N-Phenylbenzothioamide 
• 121216-11-3 3-Ethyl-6-phenyl-2-thioxo-[1,3]thiazinan-4-one 

Relevant articles and documents

Anti-HIV and Antibacterial Activities of Novel 2-(3-Substituted-4-oxo-3,4-dihydroquinazolin-2-yl)-2,3-dihydrophthalazine-1,4-diones

Abstract: In the present study, we have synthesized a series of novel 2-(3-substituted-4-oxo-3,4-dihydroquinazolin-2-yl)-2,3-dihydrophthalazine-1,4-diones by the reaction of 3-(substituted)-2-hydrazino-quinazoline-4(3H)-ones with phthalic anhydride. The starting material 3-(substituted)-2-hydrazino-quinazolin-4(3H)-ones were synthesized from various primary amines. All the synthesized compounds were screened for their antitubercular, anti-HIV and antibacterial activity against different gram positive and gram negative strains by agar dilution method. Among the test compounds, 2-(3-(4-chlorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)-2,3-dihydrophthalazine-1,4-dione (QCT7) shown most potent antibacterial activity against E. coli, and S. aureus with the MIC of 3 μg/mL. The compound QCT7 exhibited the antitubercular activity with the MIC of 25 μg/mL and anti-HIV activity with the EC50 of 43.68 μM against HIV1 and HIV2 and offers potential lead for further optimization and development to new antitubercular and anti-HIV agents. The results obtained from this study confirm that the synthesized and biologically evaluated quinazolines showed promising antimicrobial, antitubercular and anti-HIV activities and are new scaffolds for antimicrobial activity.

Soil fumigant and synthesis method and application thereof

The invention discloses a soil fumigant. The soil fumigant is an aqueous solution, and the chemical name of the effective component is sodium N-ethyldithiocarbamate. The chemical structural formula ofthe aqueous solution is shown in the specification, and the preparation method of the aqueous solution is any one of the following two methods: method 1, dropwise adding carbon disulfide into a monoethylamine aqueous solution, continuously reacting after dropwise adding to obtain an N-ethyldithiocarbamic acid aqueous solution, and dropwise adding a sodium hydroxide aqueous solution to obtain a soil fumigant, and a method 2: mixing water, a sodium hydroxide aqueous solution and a monoethylamine aqueous solution, dropwise adding carbon disulfide, and obtaining the soil fumigant after the reaction is finished. The soil fumigant prepared by the invention has the characteristics of good stability, high preparation yield and cheap and easily available raw materials, and can replace metham, theapplication method and the action principle of the soil fumigant are the same as those of metham, and root-knot nematodes, harmful bacteria and weeds do not generate cross resistance to the product disclosed by the invention, so that the purpose of thoroughly disinfecting soil is achieved.