13042-33-6

Basic information

• Product Name: glycohyodeoxycholic acid
• Synonyms: Hyodeoxycholylglycine;N-(3α,6α-Dihydroxy-24-oxo-5β-cholan-24-yl)glycine;Glycine Hyodeoxycholate;Glycylhyodeoxycholic Acid;N-(3α,6α-Dihydroxy-5β-cholan-24-oyl)glycine;N-[(3α,5β,6α)-3,6-Dihydroxy-24-oxocholan-24-yl]glycine
• CAS NO: 13042-33-6
• Molecular Formula: C26H43NO5
• Molecular Weight: 449.628
• Product Categories: Amino Acids & Derivatives;Steroids
• Mol File: 13042-33-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 655.6°Cat760mmHg
• Flash Point: 350.3°C
• Appearance: /
• Density: 1.162g/cm³
• Vapor Pressure: 5.74E-20mmHg at 25°C
• Refractive Index: 1.546
• PKA: 3.58±0.10(Predicted)
• CAS DataBase Reference: glycohyodeoxycholic acid(CAS DataBase Reference)
• NIST Chemistry Reference: glycohyodeoxycholic acid(13042-33-6)
• EPA Substance Registry System: glycohyodeoxycholic acid(13042-33-6)

Safety Data

• Hazardous Substances Data: 13042-33-6(Hazardous Substances Data)

Usage

Description

Glycohyodeoxycholic acid is a glycine-conjugated bile acid derivative that plays a crucial role in the transport and absorption of lipids and cholesterol in the intestine. It is an off-white solid with unique chemical properties that make it suitable for various applications in different industries.

Uses

Used in Pharmaceutical Industry:
Glycohyodeoxycholic acid is used as a therapeutic agent for the treatment of various liver and gallbladder disorders. Its ability to facilitate the biological transport of Hyodeoxycholate within the intestine helps improve bile flow and reduce the risk of gallstone formation.
Used in Drug Delivery Systems:
Glycohyodeoxycholic acid can be used as a carrier molecule in drug delivery systems, particularly for hydrophobic drugs. Its amphiphilic nature allows it to form micelles, which can encapsulate and solubilize hydrophobic drugs, enhancing their bioavailability and therapeutic efficacy.
Used in Cosmetic Industry:
Glycohyodeoxycholic acid can be used as an active ingredient in cosmetic products, such as creams and lotions, for its potential skin benefits. Its ability to modulate lipid metabolism may contribute to improved skin hydration, elasticity, and overall health.
Used in Food Industry:
Glycohyodeoxycholic acid can be used as a food additive to improve the digestion and absorption of dietary fats and cholesterol. Its presence in food products may help reduce the risk of developing gallstones and other related health issues.

InChI:InChI=1/C26H43NO5/c1-15(4-7-23(30)27-14-24(31)32)18-5-6-19-17-13-22(29)21-12-16(28)8-10-26(21,3)20(17)9-11-25(18,19)2/h15-22,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32)/t15-,16-,17+,18-,19+,20+,21+,22+,25-,26-/m1/s1