13045-94-8 Usage
General Description
4-[Bis(2-chloroethyl)amino]-D-phenylalanine, also known as Sarcolysin or L-Phenylalanine Mustard (L-PAM), is a chemical compound used primarily in the treatment of cancer. This synthetic compound is an alkylating agent, which means it works by interfering with the DNA in cells, causing them to die. It has shown efficacy against a variety of cancers, particularly those of the blood and lymphatic systems. Its most common side effects are related to bone marrow suppression, causing symptoms such as anemia, neutropenia, and thrombocytopenia. Despite its potential toxicity, its anticancer properties have made it a key chemotherapy agent for certain conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 13045-94-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,0,4 and 5 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 13045-94:
(7*1)+(6*3)+(5*0)+(4*4)+(3*5)+(2*9)+(1*4)=78
78 % 10 = 8
So 13045-94-8 is a valid CAS Registry Number.
13045-94-8Relevant articles and documents
Process Of Making Optically Pure Melphalan
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Page/Page column 5, (2009/10/01)
This invention provides a process of making 4-(bis-(2-hydroxyethyl)amino)-L-phenylalanine of the formula by hydroxyethylation, in a regioselective manner, of the aromatic amino group rather than the glycinic amino group.
