130464-52-7 Usage
Description
(2R,3S)-3-exo-methoxycarbonyl-7-oxabicyclo[2.2.1]heptane-2-exo-carboxylic acid is a bicyclic organic compound characterized by its unique molecular shape and specific stereochemistry. It features a carboxylic acid functional group and a methoxycarbonyl group at the third position, with the R configuration at the second position and the S configuration at the third position. (2R,3S)-3-exo-methoxycarbonyl-7-oxabicyclo[2.2.1]heptane-2-exo-carboxylic acid's constrained structure, derived from the bicyclo[2.2.1]heptane core, may offer potential applications in organic synthesis or pharmaceutical research.
Uses
Used in Organic Synthesis:
(2R,3S)-3-exo-methoxycarbonyl-7-oxabicyclo[2.2.1]heptane-2-exo-carboxylic acid is used as a building block in organic synthesis for its unique molecular shape and functional groups. The carboxylic acid group allows for the formation of derivatives with different properties, making it a versatile component in the creation of new compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (2R,3S)-3-exo-methoxycarbonyl-7-oxabicyclo[2.2.1]heptane-2-exo-carboxylic acid is used as a potential candidate for drug development due to its specific stereochemistry and constrained molecular structure. These features may contribute to its interaction with biological targets, offering opportunities for the design of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 130464-52-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,0,4,6 and 4 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 130464-52:
(8*1)+(7*3)+(6*0)+(5*4)+(4*6)+(3*4)+(2*5)+(1*2)=97
97 % 10 = 7
So 130464-52-7 is a valid CAS Registry Number.
130464-52-7Relevant articles and documents
Sealed tube promoted coupling of camptothecin and norcantharidin acid ester and their preliminary biological activity evaluation in vitro
Wang, Xian H.,Yang, Fu H.,Zhao, Chang K.,Gao, Lei,Li, Chan
, p. 406 - 411 (2018)
A facile synthetic method was developed for the novel acid-sensitive camptothecin norcantharidin acid ester derivatives 3 in sealed tube. This method offers several advantages including high yield and simple work procedure which can be extended for the synthesis of analogs. The new synthetic compounds 3 have shown better activity against several tumor cell lines in vitro test.
[4 + 2] Cycloadditions of rigid s-cis dienes to C60. A synchronous Diels-Alder reaction
Chronakis, Nikos,Orfanopoulos, Michael
, p. 545 - 548 (2007/10/03)
(Matrix presented) The Diels-Alder reaction of rigid s-cis dienes with C60 occurs by a concerted mechanism, via a symmetrical transition state.
