130480-98-7

Basic information

• Product Name: (4-{[(S)-6-Methyl-5-((R)-8-oxo-6,8-dihydro-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-6-yl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-9-ylmethyl]-carbamoyl}-phenyl)-carbamic acid tert-butyl ester
• CAS NO: 130480-98-7
• Molecular Weight: 615.64
• Mol File: 130480-98-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-{[(S)-6-Methyl-5-((R)-8-oxo-6,8-dihydro-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-6-yl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-9-ylmethyl]-carbamoyl}-phenyl)-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4-{[(S)-6-Methyl-5-((R)-8-oxo-6,8-dihydro-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-6-yl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-9-ylmethyl]-carbamoyl}-phenyl)-carbamic acid tert-butyl ester(130480-98-7)
• EPA Substance Registry System: (4-{[(S)-6-Methyl-5-((R)-8-oxo-6,8-dihydro-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-6-yl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-9-ylmethyl]-carbamoyl}-phenyl)-carbamic acid tert-butyl ester(130480-98-7)

Safety Data

• Hazardous Substances Data: 130480-98-7(Hazardous Substances Data)

Upstream product

• 485-49-4 bicuculline 
• 130480-93-2 6-(9'-chloromethyl-6'-methyl-5',6',7',8'-tetrahydro-1',3'-dioxolo<4,5-g>isoquinolin-5'-yl)furo<3,4-e>-1,3-benzodioxol-8(6H)-one 
• 67917-51-5 2,5-dioxopyrrolidin-1-yl 4-(tert-butoxycarbonylamino)benzoate 
• 130480-96-5 6-(9'-aminomethyl-6'-methyl-5',6',7',8'-tetrahydro-1',3'-dioxolo<4,5-g>isoquinolin-5'-yl)furo<3,4-e>-1,3-benzodioxol-8(6H)-one 

Relevant articles and documents

Synthesis of Substituted (+)-Bicuculline Derivatives Through Chloromethyaltion

Treatment of the phthalide isoquinoline alkaloid (+)-bicuculline with paraformaldehyde and hydrochloric acid leads to the chloromethyl derivative (4) which can be further substituted with ammonia or piperazine.In reactions to study methods of linking bicu