13053-82-2

Basic information

• Product Name: N-(1,3-thiazol-2-yl)benzamide
• Synonyms: N-(1,3-thiazol-2-yl)benzamide
• CAS NO: 13053-82-2
• Molecular Weight: 204.252
• Mol File: 13053-82-2.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: N-(1,3-thiazol-2-yl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1,3-thiazol-2-yl)benzamide(13053-82-2)
• EPA Substance Registry System: N-(1,3-thiazol-2-yl)benzamide(13053-82-2)

Safety Data

• Hazardous Substances Data: 13053-82-2(Hazardous Substances Data)

Upstream product

• 96-50-4 2-thiazolylamine 
• 93-99-2 benzoic acid phenyl ester 
• 2719-23-5 2-acetamidothiazole 
• 98-88-4 benzoyl chloride 
• 24442-57-7 1,2-dibromoethyl acetate 
• 614-23-3 N-benzoylthiourea 
• 532-55-8 Benzoyl isothiocyanate 
• 35977-95-8 1-bromo-2-oxo-2-phenylethyl cyanide 
• 65-85-0 benzoic acid 
• 15226-74-1 dicobalt octacarbonyl 
• 591-50-4 iodobenzene 
• 13939-06-5 molybdenum hexacarbonyl 
• 1934-92-5 N-methyl-N-phenyl-benzamide 
• 611-74-5 N,N-dimethylbenzamide 

Downstream Products

• 41593-98-0 N-benzylthiazol-2-amine 
• 132380-95-1 1-(1,3-thiazol-2-yl)-5-phenyltetrazole 
• 118215-05-7 N-Thiazol-2-yl-thiobenzamide 
• 473907-48-1 Re(P(C₆H₅)3)2Cl(CO)(C₆H₅CONC₃H₂NS) 
• 473907-50-5 Re(N₂CO(C₆H₅))(P(C₆H₅)3)2Cl(C₃H₂NSNC(O)C₆H₅) 
• 51579-06-7 2-phenyl-1,3-thiazolo<3,2-b><1,2,4>triazole 
• 50979-41-4 8-benzyl-6-methyl-5,7-dioxo-5,6,7,8-tetrahydro-thiazolo[3,2-a]pyrimidinylium betaine 
• 50979-36-7 8-benzyl-5,7-dioxo-5,6,7,8-tetrahydro-thiazolo[3,2-a]pyrimidinylium betaine 
• 51578-92-8 3-amino-2-benzoylamino-thiazolium; 2,4,6-trimethyl-benzenesulfonate 

Relevant articles and documents

A novel and efficient amidation of 2-aminothiazole

A facile and efficient method has been developed for the synthesis of novel thiazolyl carboxamide derivatives by direct reaction of the corresponding esters and 2-aminothiazole. Treatment of 2-aminothiozole with various carboxylic esters in the presence of t-butylmagnesium chloride provides the biologically significant thiazolyl carboxamide derivatives in good to excellent yields.

Design, synthesis and biological evaluation of new 1,3-thiazole derivatives as potential anti-inflammatory agents

Thiazoles are widely recognized as nuclei of great value for obtaining molecules with various biological activities, including analgesic, anti-inflammatory, anti-HIV, antidiabetic, antitumor and antimicrobial. A library of 26 thiazole derivatives as fragments were designed, synthesized and evaluated for their anti-inflammatory activities. Some screened compounds showed promising results and were found to be potent in the series by inhibiting LPS-induced TNFα and IL-8 release with IC50 values in μM range without cytotoxic activity.

Solar and visible-light active nano Ni/g-C3N4photocatalyst for carbon monoxide (CO) and ligand-free carbonylation reactions

In this study, we investigate the amino and alkoxycarbonylation reaction between various substituted aryl halides, benzyl iodides, and iodocyclohexane with different types of amines and alcohols in the absence of carbon monoxide gas and ligands. Similar reactions are carried out at high temperatures, in the presence of appropriate ligands, stoichiometric amounts of bases, and gaseous carbon monoxide, which endanger the health of organic chemists. We present a novel method that does not utilize ligands, bases, gaseous CO, and special conditions. This procedure is a redox reaction carried out by new economic nano Ni/g-C3N4at room temperature and under visible light. Mo(CO)6was used toin situgenerate CO, to resolve the problems caused by the use of CO gas. This protocol has the ability to be used on a gram scale by using a continuous flow reactor.

N-(thiazol-2-yl)benzamide derivatives as a new series of supramolecular gelators: Role of methyl functionality and S?O interaction

A new series of N-(thiazol-2-yl) benzamide derivatives were synthesized, characterized and investigated for their gelation behavior with the aim to elucidate the role of methyl functionality and multiple non-covalent interactions on gelation/non-gelation