130672-98-9Relevant articles and documents
Dianilinophthalimides: Potent and selective, ATP-competitive inhibitors of the EGF-receptor protein tyrosine kinase
Trinks,Buchdunger,Furet,Kump,Mett,Meyer,Muller,Regenass,Rihs,Lydon,Traxler
, p. 1015 - 1027 (2007/10/02)
Dianilinophthalimides represent a novel class of inhibitors of the EGF- receptor protein tyrosine kinase with a high degree of selectivity versus other tyrosine and serine/threonine kinases. Steady-state kinetic analysis of compound 3, which showed potent