130721-56-1Relevant articles and documents
Synthesis of N-substituted-4-methylene-oxazolidinones via base-catalyzed cyclization of propargylic alcohols with p-toluenesulfonyl isocyanate
Guo, Yue-Meng,Pi, Shao-Feng,Sun, Han-Zhou,Yi, Bing,Zhou, Zheng-Rui
, p. 521 - 523 (2020/03/23)
A practical method is developed for the synthesis of oxazolidinone derivatives, an important class of heterocyclic compounds. The effect of bases and solvents on this cyclization reaction is discussed and a simple new base–solvent system (triethylamine in toluene) is found to be the most effective. The reaction conditions developed here are mild and no by-products are observed. Moreover, using optimized conditions, a number of differently substituted propargylic alcohols are cyclized to the corresponding N-substituted-4-methylene-oxazolidinones in yields of up to 99%.
Copper-catalyzed domino cyclization of propargylic alcohol with tosyl isocyanate to oxazolidinones
Chen, Xiu-Shuai,Hou, Chuan-Jin,Liu, Yan-Jun,Yang, Rui-Feng,Hu, Xiang-Ping
supporting information, p. 173 - 177 (2017/01/10)
A copper-catalyzed domino cyclization of propargylic alcohols with tosyl isocyanate for the synthesis of oxazolidinones has been developed. Various propargylic alcohols with an aryl or alkyl substituents worked smoothly to afford the corresponding oxazoli
A Facile Preparation of 4-Alkylidene-3-tosyloxazolidin-2-ones from Propargylic Alcohols and p-Toluenesulfonyl Isocyanate Using a CuI/Et3N Catalyst
Ohe, Kouichi,Ishihara, Toshihisa,Chatani, Naoto,Kawasaki, Yoshikane,Murai, Shinji
, p. 2267 - 2268 (2007/10/02)
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