1307296-48-5

Basic information

• Product Name: (R,S)-N-Benzyl-N-(1-phenylethyl)-p-toluenesulfinamide
• Synonyms: (R,S)-N-Benzyl-N-(1-phenylethyl)-p-toluenesulfinamide
• CAS NO: 1307296-48-5
• Molecular Weight: 349.497
• Mol File: 1307296-48-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R,S)-N-Benzyl-N-(1-phenylethyl)-p-toluenesulfinamide(CAS DataBase Reference)
• NIST Chemistry Reference: (R,S)-N-Benzyl-N-(1-phenylethyl)-p-toluenesulfinamide(1307296-48-5)
• EPA Substance Registry System: (R,S)-N-Benzyl-N-(1-phenylethyl)-p-toluenesulfinamide(1307296-48-5)

Safety Data

• Hazardous Substances Data: 1307296-48-5(Hazardous Substances Data)

Upstream product

• 824-79-3 sodium 4-methylbenzenesulfinate 
• 1307296-50-9 (R,S)-N-benzyl-N-(1-phenylethyl)-p-fluorobenzenesulfinamide 
• 1307296-49-6 (R,S)-N-benzyl-N-(1-phenylethyl)-p-chlorobenzenesulfinamide 
• 1307296-47-4 (R,S)-N-benzyl-N-(1-phenylethyl)benzenesulfinamide 
• 10439-23-3 4-methylbenzenesulfinyl chloride 
• 38235-77-7 (R)-N-benzyl-1-phenylethylamine 

Downstream Products

• 38235-77-7 (R)-N-benzyl-1-phenylethylamine 
• 64396-66-3 methyl (R)-4-methylbenzenesulfinate 
• 59203-01-9 (S)-(+)-1-methyl 4-methylbenzenesulfinate 
• 20288-49-7 (S)-1-(butylsulfinyl)-4-methylbenzene 
• 1307296-51-0 (R,R)-N-benzyl-N-(1-phenylethyl)benzenesulfinamide 
• 1307296-47-4 (R,S)-N-benzyl-N-(1-phenylethyl)benzenesulfinamide 
• 1307296-53-2 (R,R)-N-benzyl-N-(1-phenylethyl)-p-chlorobenzenesulfinamide 
• 1307296-49-6 (R,S)-N-benzyl-N-(1-phenylethyl)-p-chlorobenzenesulfinamide 
• 1307296-54-3 (R,R)-N-benzyl-N-(1-phenylethyl)-p-fluorobenzenesulfinamide 
• 1307296-50-9 (R,S)-N-benzyl-N-(1-phenylethyl)-p-fluorobenzenesulfinamide 
• 188447-91-8 (S)-p-toluenesulfinimide 

Relevant articles and documents

Practical and highly stereoselective method for the preparation of several chiral arylsulfinamides and arylsulfinates based on the spontaneous crystallization of diastereomerically pure N-benzyl-N-(1-phenylethyl)- arylsulfinamides

A novel and simple process for the preparation of enantiomerically pure (SS)-benzenesulfinamide (SS)-3a, (SS)-p- toluenesulfinamide (SS)-3b, (SS)-p-chloro- benzenesulfinamide (SS)-3c and (SS)-p- fluorobenzenesulfinamide (SS)-3d has been developed. The treatment of arylsulfinyl chlorides with (R)-N-benzyl-1-phenylethanamine in the presence of excess triethylamine gave diastereomeric mixtures of N-benzyl-N-(1-phenylethyl)- arylsulfinamides 1, which underwent spontaneous crystallization to furnish diastereomerically pure (R,SS)-N-benzyl-N-(1-phenylethyl)- arylsulfinamides (R,SS)-1a-1d in 28%, 29%, 27% and 31% yields, respectively. The diastereomerically pure compounds (R,SS)-1 were then converted into four enantiopure (RS)-methyl arylsulfinates (RS)-2, and finally into four enantiopure (SS)- arylsulfinamides (SS)-3 in good yields.