13080-78-9

Basic information

• Product Name: Methanone, [4-methoxy-2-(2-propenyloxy)phenyl]phenyl-
• CAS NO: 13080-78-9
• Molecular Formula: C17H16O3
• Molecular Weight: 268.312
• Mol File: 13080-78-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Methanone, [4-methoxy-2-(2-propenyloxy)phenyl]phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, [4-methoxy-2-(2-propenyloxy)phenyl]phenyl-(13080-78-9)
• EPA Substance Registry System: Methanone, [4-methoxy-2-(2-propenyloxy)phenyl]phenyl-(13080-78-9)

Safety Data

• Hazardous Substances Data: 13080-78-9(Hazardous Substances Data)

Upstream product

• 1159707-78-4 (2-allyloxy-4-methoxyphenyl)phenylmethanol 
• 131-57-7 Benzophenone-3 
• 106-95-6 allyl bromide 

Downstream Products

• 1159707-89-7 2-allyloxy-4-methoxy-1-(1-phenylvinyl)benzene 
• 134617-18-8 (Z)-9-Methoxy-6-phenyl-4H,6H-benzo[b][1,5]oxathiocine 
• 121150-36-5 (2-Allyloxy-4-methoxy-phenyl)-phenyl-methanethione 

Relevant articles and documents

Thermally-Induced Intramolecular [4+2] Cycloaddition of Allylamino- or Allyloxy-Tethered Alkylidenecyclopropanes

A thermally-induced intramolecular [4+2] cycloaddition reaction of allylamino- or allyloxy-tethered alkylidenecyclopropanes has been reported in this paper, giving a new protocol for the rapid construction of polycyclic skeleton molecules in moderate to e

Synthesis and evaluation of the cytotoxicities of neoflavenes

The synthesis of neoflavene and neoflavenes with methoxy substituents at different positions are described. As starting materials, various salicylaldehydes were run through sequential reactions such as O-allylation, Grignard reaction, oxidation, Wittig reaction, and ring-closing metathesis to yield the target neoflavenes in good yield. Among the prepared neoflavenes, 7-methoxy-4′-methoxyneoflavene (6e) and 8-methoxy-4′- methoxyneoflavene (6f) exhibiting potential cell toxicities against various cells were disclosed. In particular, 6f which exhibited an IC50 value of 6.5 ± 2.0 and 5.1 ± 1.1 μM against gastric carcinoma and lung carcinoma cells in vitro was found, respectively. Meanwhile, the structure and activity relationship of our synthesized neoflavenes is further discussed briefly.