130800-04-3

Basic information

• Product Name: 1,2-phenylenebis(ethane-2,1-diyl) diMethanesulfonate
• Synonyms: 1,2-phenylenebis(ethane-2,1-diyl) diMethanesulfonate;1,2-Bis(2-methylsulfonyloxyethyl)benzene
• CAS NO: 130800-04-3
• Molecular Formula: C₁₂H₁₈O₆S₂
• Molecular Weight: 322.39772
• Mol File: 130800-04-3.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2-phenylenebis(ethane-2,1-diyl) diMethanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-phenylenebis(ethane-2,1-diyl) diMethanesulfonate(130800-04-3)
• EPA Substance Registry System: 1,2-phenylenebis(ethane-2,1-diyl) diMethanesulfonate(130800-04-3)

Safety Data

• Hazardous Substances Data: 130800-04-3(Hazardous Substances Data)

Usage

Chemical structure

1,2-Phenylenebis(ethane-2,1-diyl) with two methanesulfonate groups attached

Common uses

Crosslinking agent in organic synthesis and polymer chemistry, production of resins and adhesives, manufacture of pharmaceuticals and agrochemicals

Properties

Forms strong covalent bonds with different molecules and polymers, provides high strength and durability

Importance

Wide range of applications in various industries

Upstream product

• 7500-53-0 1,2-Phenylenediacetic acid 
• 17378-99-3 2,2’-(1,2-phenylene)diethanol 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 34583-83-0 7-nitro-2,3,4,5-tetrahydro-1H-benzo[d]azepiney 
• 4424-20-8 2,3,4,5-tetrahydro-1H-3-benzazepine 
• 130800-05-4 1,2-Bis(2'-iodoethyl)benzene 

Relevant articles and documents

Compound as potassium channel modulator

The invention relates to a compound as a potassium channel modulator, which is a compound of a formula (I) or a pharmaceutically acceptable salt thereof. The compound or the pharmaceutically acceptable salt thereof is effective for curing and preventing diseases and symptoms influenced by the activity of potassium ion channels.

FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND C-MET INHIBITORS

The present invention provides a compound of formula I or II or a pharmaceutically acceptable salt form thereof, wherein R1, R2, R3, R4, R5, A1, A2, A3, A4, and A5, are as defined herein. The compounds of formula I or II have ALK and/or c-Met inhibitory activity, and may be used to treat proliferative disorders.

A New General Synthesis of Polycyclic Aromatic Compounds Based on Enamine Chemistry

Alkylation of enamines and enamine salts by benzylic and (β-haloethyl)aryl halides, respectively, followed by acidic cyclodehydration and dehydrogenation provides an efficient synthetic approach to a wide range of polycyclic aromatic compounds of diverse structural types.Specific polycyclic hydrocarbons synthesized by this route include benzo- and benzofluorene, 7H-dibenzo-, 13H-dibenzo-, and 13H-dibenzofluorene, 15H-tribenzofluorene, dibenzochrysene, benzopentaphene, indenofluorene, fluorenofluorene, octahydrodibenzanthracene, dibenzanthracene, octahydrodibenzanthracene, dibenzanthracene, picene, benzopicene, 1H-benzaceanthrylene, and 4H-cyclopentachrysene.This method with appropriate modifications appears to be potentially broader in scope than established traditional methods of polycyclic hydrocarbon synthesis.