1308338-32-0

Basic information

• Product Name: (S)-(2-(2-fluorobenzyl)-1,2,3,4-tetrahydroisoquinolin-3-yl)(1-(hydroxymethyl)-6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methanone
• Synonyms: (S)-(2-(2-fluorobenzyl)-1,2,3,4-tetrahydroisoquinolin-3-yl)(1-(hydroxymethyl)-6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methanone
• CAS NO: 1308338-32-0
• Molecular Weight: 490.575
• Mol File: 1308338-32-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-(2-(2-fluorobenzyl)-1,2,3,4-tetrahydroisoquinolin-3-yl)(1-(hydroxymethyl)-6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(2-(2-fluorobenzyl)-1,2,3,4-tetrahydroisoquinolin-3-yl)(1-(hydroxymethyl)-6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methanone(1308338-32-0)
• EPA Substance Registry System: (S)-(2-(2-fluorobenzyl)-1,2,3,4-tetrahydroisoquinolin-3-yl)(1-(hydroxymethyl)-6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methanone(1308338-32-0)

Safety Data

• Hazardous Substances Data: 1308338-32-0(Hazardous Substances Data)

Upstream product

• 1308338-99-9 (S)-tert-butyl 3-(1-(hydroxymethyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 1308338-97-7 (S)-2-tert-butyl 3-perfluorophenyl 3,4-dihydroisoquinoline-2,3(1H)-dicarboxylate 
• 74163-81-8 L-Tic-OH 
• 1308338-88-6 (S)-2-(2-fluorobenzyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid 
• 486-99-7 (6,7-dimethoxy-1,2,3,4-tetrahydro-1-isoquinolyl)methanol 
• 115962-35-1 (3S)-2-tert-butoxycarbonyl-1,2,3,4-tetrahydroisoquinole-3-carboxylic acid 
• 1308339-03-8 C₂₂H₂₆N₂O₄ 
• 446-52-6 2-Fluorobenzaldehyde 

Downstream Products

• 1308338-78-4 (S)-(2-(2-fluorobenzyl)-1,2,3,4-tetrahydroisoquinolin-3-yl)(1-(hydroxymethyl)-6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methanone hydrochloride 

Relevant articles and documents

HETEROCYLIC COMPOUNDS AS ANTAGONISTS OF THE OREXIN RECEPTORS

The present invention relates to a heterocyclic derivative according to formula (I) wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceutical composition comprising said heterocyclic derivatives and to their use in therapy, for instance in the treatment or prevention of disorders or diseases influenced by modulation of orexins, such as sleep disorders.