1309362-03-5

Basic information

• Product Name: C₂₆H₂₄N₂O₈S
• CAS NO: 1309362-03-5
• Molecular Weight: 524.551
• Mol File: 1309362-03-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₆H₂₄N₂O₈S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₂₄N₂O₈S(1309362-03-5)
• EPA Substance Registry System: C₂₆H₂₄N₂O₈S(1309362-03-5)

Safety Data

• Hazardous Substances Data: 1309362-03-5(Hazardous Substances Data)

Upstream product

• 70254-43-2 4-Hydroxy-2-quinolone 
• 15151-57-2 4-hydroxy-3-nitro-1,2-dihydroquinolin-2-one 
• 99459-49-1 1H-3-amino-2-oxo-4-hydroxyquinoline 

Relevant articles and documents

Synthesis and antikinetoplastid activities of 3-substituted quinolinones derivatives

A new family of quinolinone derivatives has been synthesized and evaluated for their antikinetoplastid activities against Leishmania donovani and Trypanosoma brucei brucei. Results from these structure-activity relationship studies enabled identification of compounds 3a and 4g as the most active compounds against L. donovani promastigotes and amastigotes parasites (IC 50 values in a range of 2-11 μM). Additionally, compound 3b has emerged from this study as the most active compound in the series against T. b. brucei with a MEC value of 12 μM. These three compounds are worth of further in vivo evaluation.