1309581-65-4

Basic information

• Product Name: 2-hydroxy-1-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]ethanone
• Synonyms: 2-hydroxy-1-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]ethanone
• CAS NO: 1309581-65-4
• Molecular Weight: 168.236
• Mol File: 1309581-65-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-hydroxy-1-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-1-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]ethanone(1309581-65-4)
• EPA Substance Registry System: 2-hydroxy-1-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]ethanone(1309581-65-4)

Safety Data

• Hazardous Substances Data: 1309581-65-4(Hazardous Substances Data)

Upstream product

• 1208105-24-1 (+)-verbenol acetate 
• 22339-08-8 (+)-trans-verbenol 
• 621-59-0 isovanillin 
• 66885-03-8 (+)-cis-verbenol epoxide 
• 121-33-5 vanillin 
• 7785-70-8 (+)-α-pinene 
• 473-67-6 (1R,5R)-4,6,6-trimethylbicyclo[3.1.1]hept-3-en-2-ol 
• 90582-89-1 verbenole epoxide 
• 924265-29-2 (+)-verbenone epoxide 
• 18309-32-5 Verbenone 

Relevant articles and documents

Synthesis and analgesic activity of stereoisomers of 2-(3(4)-hydroxy-4(3)-methoxyphenyl)-4,7-dimethyl-3,4,4a,5,8,8a-hexahydro-2H-chromene-4,8-diols

2-(3(4)-Hydroxy-4(3)-methoxyphenyl)-4,7-dimethyl-3,4,4a,5,8,8a-hexahydro-2H-chromene-4,8-diols were found recently to possess high analgesic activity and low acute toxicity. Stereoisomers of these compounds with high optical purity were synthesized from (+)- and (-)-α-pinenes for the first time in this work. The structure of (4S)-4b isomer was confirmed by the XRD data. Studies of analgesic activity of the resulting products demonstrated that neither the absolute configuration nor cis- or trans-arrangement of vicinal oxygen atoms plays a significant role in manifestation of analgesic effect by these isomers, while only (4S)-4b isomer, but not (4R)-4b demonstrated the analgesic effect.

Highly potent activity of (1R,2R,6S)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3- ene-1,2-diol in animal models of parkinson's disease

(1R,2R,6S)-3-Methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol 1 possesses potent antiparkinsonian activity in both MPTP and haloperidol animal models. The use of compound 1 resulted in nearly full recovery of the locomotor and exploratory activities and was as effective as the comparator agent (levodopa). All eight stereoisomers of compound 1 have been synthesized and the influence of the absolute configuration on the antiparkinsonian activity of compound 1 was shown.