130985-40-9Relevant articles and documents
Renin inhibitory peptides. Incorporation of polar, hydrophilic end groups into an active renin inhibitory peptide template and their evaluation in a human renin infused rat model and in conscious sodium-depleted monkeys
Thaisrivongs,Pals,DuCharme,Turner,DeGraaf,Lawson,Couch,Williams
, p. 633 - 642 (2007/10/02)
We previously reported that Boc-Pro-Phe-N-MeHis-Leuψ[CHOHCH2]-Ile-Amp (1) is a potent and specific inhibitor of human renin in vitro. It was shown to resist degradation by selected proteases and a rat liver homogenate. It was shown to inhibit p