131-53-3 Usage
Description
2,2'-Dihydroxy-4-methoxybenzophenone, also known as benzophenone-8 (dioxybenzone), is a yellow powder with chemical properties that make it an effective compound for various applications, particularly in the field of sunscreen formulations.
Uses
Used in Sunscreen Industry:
2,2'-Dihydroxy-4-methoxybenzophenone is used as an ultraviolet (UV) screen for its ability to absorb both UVA and UVB harmful rays, providing protection against the damaging effects of sunlight. It is an FDA-approved sunscreen chemical with an approved usage level of 3 percent in the United States.
Used in Cosmetics Industry:
2,2'-Dihydroxy-4-methoxybenzophenone is also used as a protective agent in cosmetics to prevent product degradation arising from UV-light exposure, ensuring the stability and longevity of the products.
Used in Pharmaceutical Industry:
Although not explicitly mentioned in the provided materials, 2,2'-Dihydroxy-4-methoxybenzophenone may also have potential applications in the pharmaceutical industry, possibly as an intermediate in the synthesis of other compounds or for its light-protective properties in certain medications.
Preparation
preparation by condensation of salicylic acid and m-methoxyphenol.
Reactivity Profile
An alcohol and a ketone. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides. Ketones are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.
Fire Hazard
Flash point data for 2,2'-Dihydroxy-4-methoxybenzophenone are not available. 2,2'-Dihydroxy-4-methoxybenzophenone is probably combustible.
Check Digit Verification of cas no
The CAS Registry Mumber 131-53-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,3 and 1 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 131-53:
(5*1)+(4*3)+(3*1)+(2*5)+(1*3)=33
33 % 10 = 3
So 131-53-3 is a valid CAS Registry Number.
131-53-3Relevant articles and documents
2. 2' - dihydroxy - 4 - methoxy benzophenone preparation method
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Paragraph 0028; 0029; 0032; 0033; 0036; 0037; 0040-0045, (2017/08/26)
A preparation method of 2,2'-dihydroxy-4-methoxybenzophenone comprises the following steps: synthesizing 2,2'4-trihydroxybenzophenone from salicylic acid and resorcinol, and carrying out a methylation reaction on 2,2'4-trihydroxybenzophenone and dimethyl sulfate to prepare 2,2'-dihydroxy-4-methoxybenzophenone. The method has the advantages of high purification efficiency, good separation effect of byproducts, high product purity reaching 99.5%, and realization of industrial production requirements of the above product.
Rh-catalyzed direct synthesis of 2,2′-dihydroxybenzophenones and xanthones
Rao, Maddali L. N.,Ramakrishna, Boddu S.
, p. 75505 - 75511 (2016/08/24)
An efficient rhodium-catalyzed direct synthesis of 2,2′-dihydroxybenzophenones and xanthones was developed from functionalized salicylaldehydes. This approach provides an easy access to various functionalized 2,2′-dihydroxybenzophenone and xanthone core s
A composition for lightening skin and hair
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, (2014/10/28)
Suggested is a composition comprising (a) sclareolide and (b1) at least one tyrosinase inhibitor; and/or (b2) at least one sun protection factor; and/or (b3) at least one anti-oxidants; and/or (b4) at least one anti-inflammatory agent; and/or (b5) at least one desquamating agent.