1310562-48-1Relevant articles and documents
Polymeric Encapsulation of Novel Homoleptic Bis(dipyrrinato) Zinc(II) Complexes with Long Lifetimes for Applications as Photodynamic Therapy Photosensitisers
Karges, Johannes,Basu, Uttara,Blacque, Olivier,Chao, Hui,Gasser, Gilles
, p. 14334 - 14340 (2019)
The use of photodynamic therapy (PDT) to treat cancer has received increasing attention over the last years. However, the clinically used photosensitisers (PSs) have some limitations that include poor aqueous solubility, hepatotoxicity, photobleaching, aggregation, and slow clearance from the body, so the design of new classes of PSs is of great interest. We present the use of bis(dipyrrinato)zinc(II) complexes with exceptionally long lifetimes as efficient PDT PSs. Based on the heavy-atom effect, intersystem crossing of these complexes changes the excited state from singlet to a triplet state, thereby enabling singlet oxygen generation. To overcome the limitation of quenching effects in water and improve water solubility, the lead compound 3 was encapsulated in a polymer matrix. It showed impressive phototoxicity upon irradiation at 500 nm in various monolayer cancer cells as well as 3D multicellular tumour spheroids, without observed dark toxicity.
Catalyst Halogenation Enables Rapid and Efficient Polymerizations with Visible to Far-Red Light
Stafford, Alex,Ahn, Dowon,Raulerson, Emily K.,Chung, Kun-You,Sun, Kaihong,Cadena, Danielle M.,Forrister, Elena M.,Yost, Shane R.,Roberts, Sean T.,Page, Zachariah A.
supporting information, p. 14733 - 14742 (2020/10/13)
The driving of rapid polymerizations with visible to near-infrared light will enable nascent technologies in the emerging fields of bio- and composite-printing. However, current photopolymerization strategies are limited by long reaction times, high light
A reaction-based chromogenic and fluorescent chemodosimeter for fluoride anions
Fu, Li,Jiang, Feng-Lei,Fortin, Daniel,Harvey, Pierre D.,Liu, Yi
supporting information; experimental part, p. 5503 - 5505 (2011/06/21)
An innovative trihexylsilylacetylene-containing BODIPY dye was designed and proved to be a highly selective, sensitive, and fast chromogenic and fluorescent chemodosimeter for fluorides.