1310679-90-3Relevant articles and documents
Synthesis, chemical properties, and antimicrobial activity of 2- and 2,3-substituted [(tetrahydro-2,4-dioxopyrimidin-1(2H)-yl)phenoxy]naphthalene-1, 4-diones
Voskiene, Ausra,Sapijanskaite, Birute,Mickevicius, Vytautas,Kantminiene, Kristina,Stasevych, Maryna,Komarovska-Porokhnyavets, Olena,Musyanovych, Rostyslav,Novikov, Volodymyr
, p. 529 - 537 (2011/12/22)
Mono- and disubstituted [(tetrahydro-2,4-dioxopyrimidin-1(2H)-yl)phenoxy] naphthalene-1,4-diones were synthesized by the reaction of dihydro-1-(3-hydroxy- and 4-hydroxyphenyl)pyrimidine-2,4(1H,3H)-diones and their 5- and 6-methyl derivatives with 2,3-dichloro-1,4-naphthoquinone. Their stability in alkaline and acidic media was investigated. Four of the compounds exhibited good antimicrobial activity against Staphylococcus aureus, Mycobacterium luteum, Candida tenuis, and Aspergillus niger. Graphical abstract: [Figure not available: see fulltext.]