1310689-78-1

Basic information

• Product Name: 9-methylisoindolo[1,2-b]quinazolin-12(10H)-one
• Synonyms: 9-methylisoindolo[1,2-b]quinazolin-12(10H)-one
• CAS NO: 1310689-78-1
• Molecular Weight: 248.284
• Mol File: 1310689-78-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 9-methylisoindolo[1,2-b]quinazolin-12(10H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 9-methylisoindolo[1,2-b]quinazolin-12(10H)-one(1310689-78-1)
• EPA Substance Registry System: 9-methylisoindolo[1,2-b]quinazolin-12(10H)-one(1310689-78-1)

Safety Data

• Hazardous Substances Data: 1310689-78-1(Hazardous Substances Data)

Upstream product

• 6587-24-2 methyl 2-cyanobenzoate 
• 65658-16-4 2-amino-6-methylbenzyl alcohol 

Relevant articles and documents

A concise and cascade synthesis of batracylin and substituted isoindolo-[1,2- b ]quinazolin-12(10 H)-ones

A concise, highly convergent, and practical synthesis of the clinical-phase anticancer agent batracylin in a two-stage process in excellent yield is described. The B and C rings of this tetracyclic heterocycle are constructed by cascade cyclization of 5-nitro-2-aminobenzyl alcohol with 2-cyanomethyl benzoate in trifluoroacetic acid in good yield in a single-pot reaction. A plausible mechanism for the cascade reaction is also proposed. As part of these studies, a range of batracylin derivatives with different substituents on the C and D rings are synthesized. Georg Thieme Verlag Stuttgart.