1310812-55-5

Basic information

• Product Name: (S)-2-(2-{4-[3-(2,5-dioxo-2,5-dihydro-(1H)-pyrrole-1-yl)propanamido]benzyl}-4,7-bis(carboxy-methyl)-1,4,7-triazacylononane)acetic acid
• Synonyms: (S)-2-(2-{4-[3-(2,5-dioxo-2,5-dihydro-(1H)-pyrrole-1-yl)propanamido]benzyl}-4,7-bis(carboxy-methyl)-1,4,7-triazacylononane)acetic acid
• CAS NO: 1310812-55-5
• Molecular Weight: 559.576
• Mol File: 1310812-55-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-(2-{4-[3-(2,5-dioxo-2,5-dihydro-(1H)-pyrrole-1-yl)propanamido]benzyl}-4,7-bis(carboxy-methyl)-1,4,7-triazacylononane)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(2-{4-[3-(2,5-dioxo-2,5-dihydro-(1H)-pyrrole-1-yl)propanamido]benzyl}-4,7-bis(carboxy-methyl)-1,4,7-triazacylononane)acetic acid(1310812-55-5)
• EPA Substance Registry System: (S)-2-(2-{4-[3-(2,5-dioxo-2,5-dihydro-(1H)-pyrrole-1-yl)propanamido]benzyl}-4,7-bis(carboxy-methyl)-1,4,7-triazacylononane)acetic acid(1310812-55-5)

Safety Data

• Hazardous Substances Data: 1310812-55-5(Hazardous Substances Data)

Upstream product

• 55750-62-4 3-maleimidopropionic acid N-hydroxysuccinimide ester 
• 142131-37-1 (S)-2-(4-aminobenzyl)-1,4,7-triazacyclononane-N,N',N''-triacetic acid 

Relevant articles and documents

Maleimido-functionalized NOTA derivatives as bifunctional chelators for site-specific radiolabeling

Two basic and simple synthetic routes for mono- and bis-maleimide bearing 1,4,7-triazacyclononane-N,N',N''-triacetic acid (NOTA) chelators as new bifunctional chelators are described. The syntheses are characterized by their simplicity and short reaction times, as well as practical purification methods and acceptable to very good chemical yields. The usefulness of these two synthetic pathways is demonstrated by the preparation of a set of mono- and bis-maleimide functionalized NOTA derivatives. In conclusion, these two methods can easily be expanded to the syntheses of further tailored maleimide-NOTA chelators for diverse applications.