131086-90-3Relevant articles and documents
Synthesis and X-ray crystal structure of cynandione B analogues
Hong, Lisa P. T.,White, Jonathan M.,Donner, Christopher D.
, p. 58 - 64 (2012)
The synthesis of analogues of cynandione B, a phenolic acetophenone from Cynanchum taiwanianum, is described. The one-step conversion of benzochromenones to the heptacyclic spiroacetal core of cynandione B using methylmagnesium bromide is investigated and
Efficient synthesis of biaryl lactones by domino retro-Michael-aldol-lactonization reactions
Langer, Peter,Saleh, Nehad N.R.,Freifeld, Ilia
, p. 168 - 169 (2007/10/03)
Biaryl lactones were prepared by novel domino x retro-Michael-aldol-lactonization reactions of 2,3-dihydropyrans.
Sequential Directed Ortho Metalation-Boronic Acid Cross-Coupling Reactions. A General Regiospecific Route to Oxygenated Dibenzopyran-6-ones Related to Ellagic Acid
Alo, B. I.,Kandil, A.,Patil, P. A.,Sharp, M. J.,Siddiqui, M. A.,et al.
, p. 3763 - 3768 (2007/10/02)
A general regiospecific synthesis of dibenzopyran-6-one derivatives 1a,c and 8a-i related to ellagic acid is described (Scheme I, Table I).The sequence involves directed ortho metalation-boronation of benzamides 4 to give the arylboronic acids 5, which, upon palladium-catalyzed cross-coupling with alkoxybromobenzenes 6 leads to the biphenylamides 7.BBr3 demethylation followed by acid-catalyzed cyclization affords pyranone 8.In this manner, the naturally occurring dibenzopyranones 1a, autumnariol (1c), and the heterocyclic analogue 13 (Scheme III) were efficiently prepared.