1312447-90-7

Basic information

• Product Name: N-Ts-4-methyl-2-phenylaniline
• Synonyms: N-Ts-4-methyl-2-phenylaniline
• CAS NO: 1312447-90-7
• Molecular Weight: 337.442
• Mol File: 1312447-90-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-Ts-4-methyl-2-phenylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-Ts-4-methyl-2-phenylaniline(1312447-90-7)
• EPA Substance Registry System: N-Ts-4-methyl-2-phenylaniline(1312447-90-7)

Safety Data

• Hazardous Substances Data: 1312447-90-7(Hazardous Substances Data)

Upstream product

• 98-80-6 phenylboronic acid 
• 42308-28-1 2-amino-5-methylbiphenyl 
• 98-59-9 p-toluenesulfonyl chloride 
• 583-68-6 2-bromo-p-toluidine 

Downstream Products

• 1330574-17-8 ethyl 2-(5,6-dihydro-2-methyl-5-tosylphenanthridin-6-yl)acetate 
• 1426813-01-5 2-methyl-5-tosylphenanthridin-6(5H)-one 

Relevant articles and documents

Diastereoselective Synthesis of Dibenzo[b,d]azepines by Pd(II)-Catalyzed [5 + 2] Annulation of o-Arylanilines with Dienes

An efficient method for the construction of dibenzo[b,d]azepines containing two distinct stereogenic elements in a highly diastereoselective fashion is described. The key of the [5 + 2] reaction is to form a π-allylpalladium species through sequential C-H

Palladium-catalyzed oxidative insertion of carbon monoxide to N -sulfonyl-2-aminobiaryls through C-H bond activation: Access to bioactive phenanthridinone derivatives in one pot

Palladium-catalyzed oxidative carbonylation of N-sulfonyl-2-aminobiaryls through C-H bond activation and C-C, C-N bond formation under TFA-free and milder conditions has been developed. The reaction tolerates a variety of substrates and provides biologically important phenanthridinone derivatives in yields up to 94%.

Pd-catalyzed sequential C-C and C-N bond formations for the synthesis of N-heterocycles: Exploiting protecting group-directed C-H activation under modified reaction conditions

Easy & efficient: A Pd-catalyzed domino olefination/conjugate addition reaction of N-Ts-2-arylanilines with activated olefins has been achieved at ambient temperature under the newly defined reaction conditions. This process highlighted the directing effect of the N-protecting group in C-H activation, displayed broad substrate scope with wide functional group compatibility; thus rendering a straightforward entry to a wide variety of N-heterocycles such as dihydrophenanthridines.