1312778-65-6Relevant articles and documents
Enantioselective total synthesis of macrosphelides A and e
Prasad, Kavirayani R.,Gutala, Phaneendra
, p. 4514 - 4520 (2011/07/08)
Enantioselective synthesis of 16-membered trilactone macrolides, macrosphelide A and E from (S)-lactic acid is described. Key features of the synthesis include the utility of a hitherto unexplored β-ketophosphonate derived from lactic acid and Yamaguchi lactonization leading to the title compounds.