131287-05-3Relevant articles and documents
2-TOSYLOXYMETHYLCYCLANONES: RING SIZE DEPENDENCE OF FRAGMENTATION VERSUS INTRAMOLECULAR ALKYLATION
Heinz, Uwe,Adams, Elisabeth,Klintz, Ralf,Welzel, Peter
, p. 4217 - 4230 (1990)
The results reported seem to indicate, that in the presence of a nucleophilic base intramolecular alkylation is the normal reaction mode of tosyloxymethylcyclanones of type 14 and that the fragmentation reaction of five-membered compounds is the exception, probably because of the high steric energy of the alkylation transition states, e.g. of type E.
