13129-38-9

Basic information

• Product Name: 2-(methylsulfanyl)furan
• Synonyms: 2-(Methylsulfanyl)furan; 2-(methylthio)furan; furan, 2-(methylthio)-
• CAS NO: 13129-38-9
• Molecular Formula: C₅H₆OS
• Molecular Weight: 114.1655
• Mol File: 13129-38-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 149.2°C at 760 mmHg
• Flash Point: 44°C
• Density: 1.11g/cm³
• Vapor Pressure: 5.17mmHg at 25°C
• Refractive Index: 1.536
• CAS DataBase Reference: 2-(methylsulfanyl)furan(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(methylsulfanyl)furan(13129-38-9)
• EPA Substance Registry System: 2-(methylsulfanyl)furan(13129-38-9)

Safety Data

• Hazardous Substances Data: 13129-38-9(Hazardous Substances Data)

Usage

Type of compound

Heterocyclic organic compound

Classification

Furan derivative

Structural feature

Furan ring with a methylthio (methylsulfanyl) group at the 2-position

Usage

Flavoring agent in the food industry

Application

Production of savory and meaty flavors

Presence

Found in certain natural products and essential oils

Research

Studied for potential pharmacological and biological activities

Versatility

Industrial and potential medicinal applications

Upstream product

• 2786-02-9 2-lithiofuran 
• 624-92-0 Dimethyldisulphide 
• 110-00-9 furan 

Downstream Products

• 35133-77-8 2-(2-phenylethynyl)furan 
• 136093-75-9 4-Bromo-benzoic acid 4-((1R,2R,3S,4S)-3-methylsulfanylcarbonyl-bicyclo[2.2.1]hept-5-en-2-yl)-4-oxo-butyl ester 
• 136093-75-9 4-Bromo-benzoic acid 4-((1S,2R,3S,4R)-3-methylsulfanylcarbonyl-bicyclo[2.2.1]hept-5-en-2-yl)-4-oxo-butyl ester 
• 136093-73-7 4-Bromo-benzoic acid (E)-6-methylsulfanylcarbonyl-4-oxo-hex-5-enyl ester 
• 136093-71-5 4-Bromo-benzoic acid (Z)-6-methylsulfanylcarbonyl-4-oxo-hex-5-enyl ester 
• 136093-80-6 C₂₀H₂₁BrO₆S 
• 136093-69-1 4-Bromo-benzoic acid 3-(5-methylsulfanyl-furan-2-yl)-propyl ester 
• 153758-92-0 2-Methylsulfanyl-5-(1-prop-2-ynyloxy-cyclohexyl)-furan 
• 77287-72-0 2-methyl-5-(phenylthio)furan 
• 71-43-2 benzene 
• 13678-59-6 methyl 5-methyl-2-furyl sulfide 

Relevant articles and documents

Metal-free synthesis of biaryls from aryl sulfoxides and sulfonanilides via sigmatropic rearrangement

Treatment of aryl sulfoxides and sulfonanilides with trifluoroacetic anhydride resulted in the dehydrative metal-free construction of the corresponding unsymmetrical biaryls. The reaction would proceed via (1) the activation of aryl sulfoxide with the anhydride, (2) interrupted Pummerer reaction of the resulting arylsulfonium with sulfonanilide, (3) [3,3] sigmatropic rearrangement to cleave the transient S–N bond and to form the prospective biaryl C–C bond, and (4) global aromatization. The choice of the amino protecting group is crucial, and only N-sulfonylanilines, i.e., sulfonanilides, could participate in the formation of biaryls.

Structure-activity relationship (SAR) of the α-amino acid residue of potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonists

This letter describes the structure-activity relationship (SAR) of the 'right-wing' α-amino acid residue of potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonists. Novel (S)-substituted heteroaryl-bearing α-amino acids have been identified

Biotransformation of organic sulfides. Part 12. Conversion of heterocyclic sulfides to chiral sulfoxides by Helminthosporium sp. NRRL 4671 and Mortierella isabellina ATCC 42613

The enantioselective oxidation of a series of heterocyclic prochiral sulfides to chiral sulfoxides has been examined using the fungal biocatalysts Helminthosporium species NRRL 4671 and Mortierella isabellina ATCC 42613. Methylthiofuranyl and -thiophenyl