1313191-81-9

Basic information

• Product Name: 2-(3-β-D-glucopyranosyloxy-4-benzyloxyphenyl)-3,5,7-tribenzyloxy-4H-chromen-4-one
• Synonyms: 2-(3-β-D-glucopyranosyloxy-4-benzyloxyphenyl)-3,5,7-tribenzyloxy-4H-chromen-4-one
• CAS NO: 1313191-81-9
• Molecular Weight: 824.881
• Mol File: 1313191-81-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(3-β-D-glucopyranosyloxy-4-benzyloxyphenyl)-3,5,7-tribenzyloxy-4H-chromen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-β-D-glucopyranosyloxy-4-benzyloxyphenyl)-3,5,7-tribenzyloxy-4H-chromen-4-one(1313191-81-9)
• EPA Substance Registry System: 2-(3-β-D-glucopyranosyloxy-4-benzyloxyphenyl)-3,5,7-tribenzyloxy-4H-chromen-4-one(1313191-81-9)

Safety Data

• Hazardous Substances Data: 1313191-81-9(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 40554-92-5 3,7-bis(benzyloxy)-2-[4-(benzyloxy)-3-hydroxyphenyl]-5-hydroxy-4H-1-benzopyran-4-one 
• 117-39-5 quercetol 
• 1313191-80-8 2-(3-(2,3,4,6-tetra-O-acetyl)-β-D-glucopyranosyloxy-4-benzyloxyphenyl)-3,5,7-tribenzyloxy-4H-chromen-4-one 
• 357194-12-8 3,7-bisbenzyloxy-2-(3-(2,3,4,6-tetra-O-acetyl)-β-D-glucopyranosyloxy-4-benzyloxyphenyl)-5-hydroxyl-4H-chromen-4-one 

Downstream Products

• 19254-30-9 isoquercitrin 

Relevant articles and documents

Regiospecific synthesis of quercetin O-β-d-glucosylated and O-β-d-glucuronidated isomers

Quercetin, the polyphenolic compound, which has the highest daily intake, is well known for its protective effects against aging diseases and has received a lot of attention for this reason. Both quercetin 3-O-β-d-glucuronide and quercetin 3′-O-β-d-glucuronide are human metabolites, which, together with their regioisomers, are required for biological as well as physical chemistry studies. We present here a novel synthetic route based on the sequential and selective protections of the hydroxyl functions of quercetin allowing selective glycosylation, followed by TEMPO-mediated oxidation to the glucuronide. This methodology enabled us to synthesize the five O-β-d-glucosides and four O-β-d-glucuronides of quercetin, including the major human metabolite, quercetin 3-O-β-d-glucuronide.