131321-84-1 Usage
Description
(R)-3-Azido-1,2-propanediol, with the molecular formula C3H7N3O2, is a chiral compound that possesses a non-superimposable mirror image. It serves as a crucial building block in the synthesis of various organic compounds and acts as a reagent in organic synthesis processes. Its unique structure and properties make it a versatile compound of interest in both academic and industrial research and development.
Uses
Used in Pharmaceutical Industry:
(R)-3-Azido-1,2-propanediol is used as a key building block for the synthesis of pharmaceuticals, particularly in the creation of glycosidic linkages and nucleoside analogs. Its role in the development of these compounds is essential for advancing drug discovery and improving therapeutic options.
Used in Chiral Compounds Synthesis:
In the field of chiral chemistry, (R)-3-Azido-1,2-propanediol is utilized as a starting material for the preparation of chiral amino alcohols and other chiral compounds. These chiral molecules have significant applications in various industries, including pharmaceuticals, agrochemicals, and the synthesis of specialty chemicals.
Used in Organic Synthesis:
(R)-3-Azido-1,2-propanediol serves as a valuable reagent in organic synthesis, enabling the creation of a wide range of organic compounds with diverse applications. Its versatility in this field contributes to the development of new materials and compounds with potential uses in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 131321-84-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,3,2 and 1 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 131321-84:
(8*1)+(7*3)+(6*1)+(5*3)+(4*2)+(3*1)+(2*8)+(1*4)=81
81 % 10 = 1
So 131321-84-1 is a valid CAS Registry Number.
InChI:InChI=1/C3H7N3O2/c4-6-5-1-3(8)2-7/h3,7-8H,1-2H2/t3-/m1/s1
131321-84-1Relevant articles and documents
Magnesium chloride (MgCl2) catalyzed highly regioselective C-3 ring opening of 2,3 epoxy alcohols by N-nucleophile
Kumar, Amit,Panda, Gautam
supporting information, (2021/04/09)
We herein report Magnesium chloride (MgCl2) catalyzed first highly C3-selective ring-opening reaction of various 2,3-epoxy alcohols with assorted N-Nucleophiles and sodium azide to furnish 3-amino-1,2 diols and 3-azido-1,2 diols respectively in high yields under mild reaction conditions. This protocol attributes the use of catalytic amount of Magnesium chloride (MgCl2), simple reaction conditions, practical operation and broad functional group tolerance.
MACROCYCLIC COMPOUNDS FOR TREATING DISEASE
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Paragraph 0398; 0399; 0400, (2019/07/13)
The present disclosure relates to certain macrocyclic derivatives, pharmaceutical compositions containing them, and methods of using them to treat disease, such as cancer.
Synthesis and biological evaluation of novel gramicidin s analogues
Tuin, Adriaan Willem,Palachanis, Dimitrios Konstantinos,Buizert, Annelies,Grotenbreg, Gijsbert Marnix,Spalburg, Emile,De Neeling, Albert J.,Mars-Groenendijk, Roos H.,Noort, Daan,Van Der Marel, Gijsbert A.,Overkleeft, Herman S.,Overhand, Mark
experimental part, p. 4231 - 4241 (2011/02/24)
The synthesis of three new analogues of the cyclic cationic antimicrobial peptide Gramicidin S is described. These derivatives contain a modified turn region in which the DPhe-Pro motif has been replaced by a constrained furanoid sugar amino ac
