131326-91-5

Basic information

• Product Name: 4-(4-Bromo-phenyl)-2-methyl-1,2,3,4-tetrahydro-isoquinolin-4-ol
• Synonyms: 4-(4-Bromo-phenyl)-2-methyl-1,2,3,4-tetrahydro-isoquinolin-4-ol
• CAS NO: 131326-91-5
• Molecular Weight: 318.213
• Mol File: 131326-91-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(4-Bromo-phenyl)-2-methyl-1,2,3,4-tetrahydro-isoquinolin-4-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Bromo-phenyl)-2-methyl-1,2,3,4-tetrahydro-isoquinolin-4-ol(131326-91-5)
• EPA Substance Registry System: 4-(4-Bromo-phenyl)-2-methyl-1,2,3,4-tetrahydro-isoquinolin-4-ol(131326-91-5)

Safety Data

• Hazardous Substances Data: 131326-91-5(Hazardous Substances Data)

Upstream product

• 99-73-0 para-bromophenacyl bromide 
• 131326-79-9 1-(4-Bromo-phenyl)-2-[(2-iodo-benzyl)-methyl-amino]-ethanone 
• 113258-86-9 1-(2-iodophenyl)-N-methylmethanamine 

Relevant articles and documents

A convenient synthesis of 4-substituted 1,2,3,4-tetrahydroisoquinolin-4-ols by a novel intramolecular Barbier reaction and by an insertion reaction: Reaction scope and limitations

4-Substituted 1,2,3,4-tetrahydroisoquinolin-4-ols were prepared from N-(2-iodobenzyl)phenacylamines by an intramolecular Barbier reaction with butyllithium and by an insertion reaction with zerovalent nickel. The scope and limitations of these reactions were discussed.