131336-23-7 Usage
Explanation
The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 14 carbon (C) atoms, 12 hydrogen (H) atoms, 2 nitrogen (N) atoms, and 1 oxygen (O) atom.
Explanation
The compound is derived from benzimidazole, which is a fused-ring system consisting of a benzene ring and an imidazole ring. The phenylmethyl group (-CH2Ph) is attached to the second position of the benzimidazole core.
Explanation
1H-Benzimidazol-5-ol, 2-(phenylmethyl)is used as a building block in the synthesis of various organic compounds, including those with pharmaceutical and agrochemical applications.
Explanation
The compound has shown potential as a therapeutic agent, indicating that it can interact with biological systems and may have effects on living organisms.
Explanation
Due to its biological activity, 1H-Benzimidazol-5-ol, 2-(phenylmethyl)has been studied for its potential use in treating different diseases, although specific diseases are not mentioned in the provided material.
Explanation
The compound has been studied for its potential use in creating materials with tailored electronic and optical characteristics, which could be useful in various technological applications.
Chemical Structure
Benzimidazole derivative with a phenylmethyl substituent at the second position
Applications
Organic chemistry, pharmaceuticals, and agrochemicals
Biological Activity
Exhibits biological activity
Therapeutic Potential
Treatment of various diseases
Material Properties
Potential role in the development of materials with specific electronic and optical properties
Check Digit Verification of cas no
The CAS Registry Mumber 131336-23-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,3,3 and 6 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 131336-23:
(8*1)+(7*3)+(6*1)+(5*3)+(4*3)+(3*6)+(2*2)+(1*3)=87
87 % 10 = 7
So 131336-23-7 is a valid CAS Registry Number.
131336-23-7Relevant articles and documents
A novel series of benzimidazole NR2B-selective NMDA receptor antagonists
Davies, David J.,Crowe, Matthew,Lucas, Nolwenn,Quinn, Joanna,Miller, David D.,Pritchard, Sara,Grose, David,Bettini, Ezio,Calcinaghi, Novella,Virginio, Caterina,Abberley, Lee,Goldsmith, Paul,Michel, Anton D.,Chessell, Iain P.,Kew, James N.C.,Miller, Neil D.,Gunthorpe, Martin J.
, p. 2620 - 2623 (2012/05/05)
A series of novel benzimidazoles are discussed as NR2B-selective N-methyl-d-aspartate (NMDA) receptor antagonists. High throughput screening (HTS) efforts identified a number of potent and selective NR2B antagonists such as 1. Exploration of the substituents around the core of this template identified a number of compounds with high potency for NR2B (pIC50 >7) and good selectivity against the NR2A subunit (pIC50 2+ and radioligand binding studies. These agents offer potential for the development of therapeutics for a range of nervous system disorders including chronic pain, neurodegeneration, migraine and major depression.
