131395-10-3 Usage
Description
2-AMINO-5-MERCAPTO-1,3,4-THIADIAZOLE is an organic compound characterized by its unique chemical structure, which features a thiadiazole ring with an amino group at the 2nd position and a mercapto group (-SH) at the 5th position. 2-AMINO-5-MERCAPTO-1,3,4-THIADIAZOLE is known for its versatile chemical properties and potential applications in various industries.
Uses
Used in Pharmaceutical Industry:
2-AMINO-5-MERCAPTO-1,3,4-THIADIAZOLE is used as a key intermediate in the synthesis of various pharmaceutical compounds, particularly in the development of analogs of riluzole, a well-known blocker of excitatory amino acid-mediated neurotransmission. Its unique chemical structure allows for the creation of new drug candidates with potential therapeutic applications in treating neurological disorders.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2-AMINO-5-MERCAPTO-1,3,4-THIADIAZOLE serves as a valuable building block for the development of novel compounds with diverse applications. Its reactivity and functional groups enable chemists to explore new synthetic pathways and create innovative molecules for various purposes, including but not limited to, pharmaceuticals, agrochemicals, and materials science.
Used in Research and Development:
2-AMINO-5-MERCAPTO-1,3,4-THIADIAZOLE is also utilized in research and development laboratories for the study of its chemical properties, reactivity, and potential applications. Researchers can use this compound to investigate new reaction mechanisms, develop new synthetic methods, and explore its potential as a precursor for other valuable compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 131395-10-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,3,9 and 5 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 131395-10:
(8*1)+(7*3)+(6*1)+(5*3)+(4*9)+(3*5)+(2*1)+(1*0)=103
103 % 10 = 3
So 131395-10-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H14N2S/c1-11(2,3)7-4-5-8-9(6-7)14-10(12)13-8/h4-6H,1-3H3,(H2,12,13)
131395-10-3Relevant articles and documents
A facile synthesis of novel near-infrared pyrrolopyrrole aza-BODIPY luminogens with aggregation-enhanced emission characteristics
Li, Lanqing,Wang, Lingyun,Tang, Hao,Cao, Derong
, p. 8352 - 8355 (2017)
Here we report the facile synthesis of two triphenylethylene-modified pyrrolopyrrole aza-BODIPY dyes with an aggregation-enhanced emission feature. NIR-emitting nanoparticles with remarkable photostability properties and applications in bioimaging were ge
Visible-light-initiated malic acid-promoted cascade coupling/cyclization of aromatic amines and KSCN to 2-aminobenzothiazoles without photocatalyst
He, Wei-Bao,Gao, Lan-Qing,Chen, Xin-Jie,Wu, Zhi-Lin,Huang, Ying,Cao, Zhong,Xu, Xin-Hua,He, Wei-Min
supporting information, p. 1895 - 1898 (2020/02/27)
By using ambient air as the oxidant and malic acid as the promoter, a practical method for the preparation of 2-aminobenzothiazoles through visible-light-initiated cascade reaction of aromatic amines and KSCN in eco-friendly bis(methoxypropy)ether under metal-, hazardous additive-, photocatalyst-free conditions was established.
Copper-Catalyzed Aerobic Oxidative Regioselective Thiocyanation of Aromatics and Heteroaromatics
Jiang, Huanfeng,Yu, Wentao,Tang, Xiaodong,Li, Jianxiao,Wu, Wanqing
, p. 9312 - 9320 (2017/09/22)
A copper-catalyzed aerobic oxidative reaction between aromatics or heteroaromatics with KSCN is developed by using O2 as the oxidant. The combination of Cu(OTf)2, N,N,N′,N′-tetramethylethylenediamine (TMEDA) and BF3·Et2O provides an efficient catalytic system, affording substituted thiocyanation products and 2-aminobenzothiazoles in excellent yields. The reaction also possesses a good functional group tolerance for both strong electron-withdrawing and electron-donating groups.
