13141-40-7

Basic information

• Product Name: Benzenemethanol, 2-(phenylethynyl)-
• CAS NO: 13141-40-7
• Molecular Formula: C15H12O
• Molecular Weight: 208.26
• Mol File: 13141-40-7.mol
• Article Data: 40

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 2-(phenylethynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 2-(phenylethynyl)-(13141-40-7)
• EPA Substance Registry System: Benzenemethanol, 2-(phenylethynyl)-(13141-40-7)

Safety Data

• Hazardous Substances Data: 13141-40-7(Hazardous Substances Data)

Usage

Physical Appearance

White to off-white powder

Common Uses

Production of pharmaceuticals
Production of dyes
Production of other organic compounds

Application as a Ligand

Used in coordination chemistry

Role in Organic Synthesis

Acts as a building block

Investigated Biological Activities

Serotonin reuptake inhibition
Antitumor properties

Versatility

Widely applicable across various industries.

Upstream product

• 18982-54-2 o-bromobenzyl alcohol 
• 536-74-3 phenylacetylene 
• 59046-72-9 o-(phenylethynyl)benzaldehyde 
• 13146-23-1 copper(I) phenylacetylenide 
• 5159-41-1 2-iodobenzyl alcohol 
• 26260-02-6 2-iodobenzaldehyde 
• 6630-33-7 ortho-bromobenzaldehyde 
• 226089-80-1 2-(2-benzenesulfonylmethyl-phenyl)-[1,3]dioxolane 
• 226089-86-7 2-(2-(phenylethynyl)phenyl)-1,3-dioxolane 
• 468751-38-4 ortho-(phenylsulfonylmethyl)benzaldehyde 
• 57341-98-7 4-(phenylethynyl)benzaldehyde 
• 30353-46-9 5-phenyl-2,4-pentadiyn-1-ol 
• 74-86-2 acetylene 

Downstream Products

• 1205555-55-0 4-iodo-3-phenyl-1H-isochromene 
• 1205555-72-1 (Z)-1-iodophenylmethylene-1,3-dihydroisobenzofuran 
• 29539-19-3 1-(phenylmethylidene)-1,3-dihydroisobenzofuran 
• 29539-19-3 (Z)?1?benzylidene?1,3?dihydroisobenzofuran 
• 29539-10-4 3-phenyl-1H-isochromene 
• 138695-53-1 (E)-1-benzylidene-1,3-dihydroisobenzofuran 
• 467249-09-8 2-bromo-1-[2-(phenylethynyl)benzyl]-1H-indole-3-carboxaldehyde 
• 947395-59-7 1-(azidomethyl)-2-(phenylethynyl)benzene 
• 442904-01-0 1-(bromomethyl)-2-(phenylethynyl)benzene 
• 59046-72-9 o-(phenylethynyl)benzaldehyde 

Relevant articles and documents

Rapid, easy copper-free Sonogashira couplings using aryl iodides and activated aryl bromides

We present here an easy, rapid copper-free methodology for the Sonogashira coupling reaction. It works well for a range of aryl iodides and activated aryl bromides.

Accessing Polycyclic Heteroarenes Enabled by Copper-Catalyzed Aerobic Oxidative C–H/C–H [4 + 2] Annulation of 3-Arylindole Derivatives

Several polycyclic aromatic hydrocarbons are delivered at room temperature by copper-catalyzed aerobic oxidative C–H/C–H [4 + 2] annulation of alkyl-substituted 3-arylindole derivatives. Specifically, dual aryl C–H functionalization is furnished under mil

An unsymmetrical Schiff-base derived recyclable Pd-catalyst for Suzuki–Miyaura and Sonogashira reactions in aqueous media

Abstract: A water-soluble palladium (II) complex containing an unsymmetrical Schiff-base ligand was synthesized and applied as catalyst Suzuki–Miyaura and Sonogashira cross-coupling reactions in aqueous media. Notably, moderate to excellent yields of biaryls were obtained in Suzuki reaction with usually less reactive aryl and heteroaryl chlorides under relatively mild condition. Moderate-to-high yields of aryl-alkynes were also obtained in Sonogashira reactions using aryl bromides. Apart from hydrophilic nature, the accomplishment of reactions in water, high recyclability, broad functional group tolerance, etc., are other advantages of the system. Graphic abstract: [Figure not available: see fulltext.]

Regio- and stereoselective intramolecular hydroalkoxylation of aromatic alkynols: an access to dihydroisobenzofurans under transition-metal-free conditions

An efficient, transition-metal-free method to synthesize dihydroisobenzofuran derivatives via intramolecular hydroalkoxylation of aromatic alkynols with the promotion of cesium carbonate has been developed. The reaction proceeds regioselectively with exclusive formation of 5-exo-dig product, and only Z-isomer of the new generated double bond is observed. This new protocol features with milder reaction conditions, more convenient operation and satisfactory selectivities.