13141-43-0

Basic information

• Product Name: 2-(Pyridin-2-ylethynyl)aniline
• Synonyms: 2-(Pyridin-2-ylethynyl)aniline
• CAS NO: 13141-43-0
• Molecular Weight: 194.236
• Mol File: 13141-43-0.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 2-(Pyridin-2-ylethynyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Pyridin-2-ylethynyl)aniline(13141-43-0)
• EPA Substance Registry System: 2-(Pyridin-2-ylethynyl)aniline(13141-43-0)

Safety Data

• Hazardous Substances Data: 13141-43-0(Hazardous Substances Data)

Usage

General Description

2-(Pyridin-2-ylethynyl)aniline is a chemical compound with the molecular formula C13H10N2. It is a pale yellow solid that is commonly used in organic synthesis and as a building block in the production of various pharmaceuticals and agrochemicals. 2-(Pyridin-2-ylethynyl)aniline is also known for its ability to act as a ligand in coordination chemistry, forming complexes with various metal ions. Its unique structure and properties make it a versatile molecule with a wide range of potential applications in the field of chemical research and development.

Upstream product

• 1945-84-2 2-ethynylpyridine 
• 615-43-0 2-iodophenylamine 
• 77340-84-2 2-(o-nitrostyryl)-pyridine 
• 681463-39-8 2-(α,β-dichloro-2-nitro-phenethyl)-pyridine 
• 155372-21-7 2-((2-nitrophenyl)ethynyl)pyridine 
• 109-04-6 2-bromo-pyridine 
• 52670-38-9 2-ethynylaniline 

Downstream Products

• 1323111-31-4 6-(4-methoxyphenyl)-7H-benzo[f]pyrido[1,2-b][2,7]naphthyridin-7-one 
• 1323111-28-9 6-(4-fluorobenzyl)-7H-benzo[f]pyrido[1,2-b][2,7]naphthyridin-7-one 
• 1323111-23-4 6-phenethyl-7H-benzo[f]pyrido[1,2-b][2,7]naphthyridin-7-one 
• 1323111-30-3 6-phenyl-7H-benzo[f]pyrido[1,2-b][2,7]naphthyridin-7-one 
• 1323111-32-5 2-[3-(pyridin-2-yl)-4-(pyridin-2-ylmethyl)quinolin-2-yl]aniline 
• 855749-06-3 4-methyl-N-(2-(pyridin-2-ylethynyl)phenyl)benzenesulfonamide 

Relevant articles and documents

Copper-catalyzed trifluoromethylazidation and rearrangement of aniline-linked 1,7-enynes: Access to CF3-substituted azaspirocyclic dihydroquinolin-2-ones and furoindolines

A set of reactions involving copper-catalyzed trifluoromethylazidation and then rearrangement of aniline-linked 1,7-enynes with the relatively poorly reactive Togni reagent I and TMSN3 was developed, and provided facile access to structurally d

ZnBr2-mediated synthesis of indoles in a ball mill by intramolecular hydroamination of 2-alkynylanilines

A method for the intermolecular hydroamination of 2-alkynylanilines in a planetary ball mill is described, which avoids the use of solvents during the reaction. Different additives were tested, whereby ZnBr2 in stoichiometric amounts showed the best performance in terms of yield and selectivity. Furthermore, the materials used for milling balls and beakers as well as the milling time and the rotation frequency were changed in order to achieve the best reaction conditions. As a result, two methods for the synthesis of 2-substituted 1H-indoles are described with their respective advantages and disadvantages. Both methods were used to convert different alkyl and aryl containing 2-ethynylanilines. This journal is the Partner Organisations 2014.

Protonated DBU as catalyst for cascade addition-cyclization of 2-alkynylaniline and carbon disulfide

Protonated 1,8-diazabicyclo[5,4,0]undec-7-ene as catalyst for cascade addition/cyclization of 2-alkynylaniline and carbon disulfide has been described. This process provides a convenient route for synthesis of a variety of benzo[d][1,3]thiazine-2(4H)-thio