13142-86-4 Usage
Functional group
Urea group (R1R2N-C(=O)-N-R3)
R1 and R2 groups
Both hydrogens (H)
R3 group
3-ethoxyphenyl group (benzene ring attached to an ethoxy group -OCH2CH3)
Potential applications
Medicinal chemistry
Biological activities
Anti-cancer, anti-inflammatory, and anti-microbial properties
Chemical properties
The ethoxyphenyl group may impart specific chemical properties to the molecule
Biological properties
The ethoxyphenyl group may also impart specific biological properties to the molecule
Research and development
Of interest for further research and development due to its potential applications and properties
Check Digit Verification of cas no
The CAS Registry Mumber 13142-86-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,1,4 and 2 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 13142-86:
(7*1)+(6*3)+(5*1)+(4*4)+(3*2)+(2*8)+(1*6)=74
74 % 10 = 4
So 13142-86-4 is a valid CAS Registry Number.
13142-86-4Relevant articles and documents
A Straightforward Synthesis of N-Substituted Ureas from Primary Amides
Franck, Xavier,Glachet, Thomas,Ibert, Quentin,Lohier, Jean-Fran?ois,Reboul, Vincent,Saraiva Rosa, Nathalie
, p. 2099 - 2105 (2020/07/13)
A direct and convenient method for the preparation of N-substituted ureas is achieved by treating primary amides with phenyliodine diacetate (PIDA) in the presence of an ammonia source (NH 3 or ammonium carbamate) in MeOH. The use of 2,2,2-trifluoroethanol (TFE) as the solvent increases the electrophilicity of the hypervalent iodine species and allows the synthesis of electron-poor carboxamides. This transformation involves a nucleophilic addition of ammonia on the isocyanate intermediate generated in situ by a Hofmann rearrangement of the starting amide.
