131423-66-0

Basic information

• Product Name: (S,S)-((((2-(indol-3-yl)-1-(hydroxymethyl)ethyl)amino)carbonyl)-2-methylpropyl)(methyl)carbamic acid, phenylmethyl ester
• Synonyms: (S,S)-((((2-(indol-3-yl)-1-(hydroxymethyl)ethyl)amino)carbonyl)-2-methylpropyl)(methyl)carbamic acid, phenylmethyl ester
• CAS NO: 131423-66-0
• Molecular Weight: 437.539
• Mol File: 131423-66-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S,S)-((((2-(indol-3-yl)-1-(hydroxymethyl)ethyl)amino)carbonyl)-2-methylpropyl)(methyl)carbamic acid, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S,S)-((((2-(indol-3-yl)-1-(hydroxymethyl)ethyl)amino)carbonyl)-2-methylpropyl)(methyl)carbamic acid, phenylmethyl ester(131423-66-0)
• EPA Substance Registry System: (S,S)-((((2-(indol-3-yl)-1-(hydroxymethyl)ethyl)amino)carbonyl)-2-methylpropyl)(methyl)carbamic acid, phenylmethyl ester(131423-66-0)

Safety Data

• Hazardous Substances Data: 131423-66-0(Hazardous Substances Data)

Upstream product

• 42417-65-2 Z-MeVal-OH 
• 154-09-6 L-tryptophanol 

Relevant articles and documents

A Regio- and stereocontrolled total synthesis of (-)-indolactam-V

(-)-Indolactam-V (IL-V) (1)-was prepared in 10 steps from L-tryptophan methyl ester in 17.1% overall yield. The key steps involve regiospecific thallation of the acylindole intermediate (4), followed by azide displacement and reduction to introduce the 13-amino group. Control of the C-11 stereocenter was achieved by SN2 displacement of the chiral inflate (10), derived from D-valine. The thallium mediated closure of dipeptide (17) did not provide an alternative route to IL-V.