1314556-94-9

Basic information

• Product Name: 5-hydroxy-1-[1-((S)-phenyl)-ethyl]-4-n-propyl-1,5-dihydro-pyrrol-2-one
• Synonyms: 5-hydroxy-1-[1-((S)-phenyl)-ethyl]-4-n-propyl-1,5-dihydro-pyrrol-2-one
• CAS NO: 1314556-94-9
• Molecular Weight: 245.321
• Mol File: 1314556-94-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5-hydroxy-1-[1-((S)-phenyl)-ethyl]-4-n-propyl-1,5-dihydro-pyrrol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-hydroxy-1-[1-((S)-phenyl)-ethyl]-4-n-propyl-1,5-dihydro-pyrrol-2-one(1314556-94-9)
• EPA Substance Registry System: 5-hydroxy-1-[1-((S)-phenyl)-ethyl]-4-n-propyl-1,5-dihydro-pyrrol-2-one(1314556-94-9)

Safety Data

• Hazardous Substances Data: 1314556-94-9(Hazardous Substances Data)

Upstream product

• 2627-86-3 (S)-1-phenyl-ethylamine 
• 78920-10-2 5-hydroxy-4-n-propyl-2,5-dihydrofuran-2-one 
• 110-62-3 pentanal 

Downstream Products

• 1355169-44-6 3-propyl-4-((S)-1'-phenylethylamino)butanoic acid 
• 1315473-74-5 (R,S)-3-[(1-phenylethylamino)-methyl]-hexanoic acid hydrochloride 
• 1314557-04-4 (3R)-3-propyl-4-((S)-1'-phenylethylamino)butanoic acid 
• 1314557-03-3 (3S)-3-propyl-4-((S)-1'-phenylethylamino)butanoic acid 

Relevant articles and documents

THREE COMPONENT CO-CRYSTAL FORMATION BETWEEN DIASTEREOMERIC MIXTURES OF 3-ALKYL-4-((S)-1'PHENYLETHYLAMINO) BUTANOIC ACID AND OPTICALLY PURE 1, 1'-BI-2-NAPHTHOL

A ternary co-crystal consisting of 1 :0.5:0.5 molar proportion of (S)-1,1'-bi-2-naphthol, 3(S)-propyl-4-[(S)1 '-phenyl-ethylamino]-butanoic acid and 3(R)-propyl-4-[(S)1'- phenyl-ethylamino]-butanoic acid having characteristic powder X-ray diffraction pattern with 2Θ values of 8.41, 9.38, 10.32, 12.16, 15.52, 15.51, 17.84, 17.95, 19.16, 20.37, 21.74, 22.55, 24.44, 25.65, 28.40, 29.15, 29.69, 31.31, 33.54, 34.40, 35.43 (±0.2) and having differential scanning calorimetric peak at about 189.23 ° C when analyzed at the rate of heating of 10°C per minute and process for preparing the same. A process for resolution of (S)-1,1'-bi-2-naphthol from RS-1,1'-bi-2-naphthol.

METHOD FOR PREPARATION OF ENANTIOMERICALLY ENRICHED AND/OR RACEMIC GAMMA-AMINO ACIDS

A process for preparation of enantiomerically enriched and/or racemic γ-amino acids, particularly those useful for preparing γ-amino acids that exhibit binding affinity to the human α2δ calcium channel subunit, including pregabalin and related compounds such as 3-n-propyl-4-aminobutyric acid.