1315054-87-5 Usage
Description
(R)-3-Hydroxy-N,N-diMethylpyrrolidine-1-carboxaMide is a chiral derivative of pyrrolidine, a heterocyclic organic compound, characterized by its highly polar nature due to the presence of a hydroxy group and a carboxamide group. The "R" in its name signifies that it is the enantiomer with a right-handed rotation. (R)-3-Hydroxy-N,N-diMethylpyrrolidine-1-carboxaMide is widely recognized for its applications as a chiral auxiliary in organic synthesis for the preparation of chiral molecules and for its potential pharmaceutical applications, particularly as a building block for the synthesis of drugs and other bioactive compounds. Its unique properties make it a valuable reagent in chemical research and drug development.
Uses
Used in Pharmaceutical Industry:
(R)-3-Hydroxy-N,N-diMethylpyrrolidine-1-carboxaMide is used as a building block for the synthesis of drugs and other bioactive compounds, leveraging its chiral properties to create enantiomerically pure pharmaceuticals that can target specific biological receptors with high selectivity.
Used in Organic Synthesis:
In the field of organic synthesis, (R)-3-Hydroxy-N,N-diMethylpyrrolidine-1-carboxaMide serves as a chiral auxiliary, aiding in the preparation of chiral molecules with precise stereochemistry. This is crucial for the development of compounds with desired biological activities and minimizing potential side effects.
Used in Chemical Research:
(R)-3-Hydroxy-N,N-diMethylpyrrolidine-1-carboxaMide is utilized as a valuable reagent in chemical research, contributing to the advancement of our understanding of molecular interactions, stereoselective synthesis, and the development of novel synthetic methodologies.
Check Digit Verification of cas no
The CAS Registry Mumber 1315054-87-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,5,0,5 and 4 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1315054-87:
(9*1)+(8*3)+(7*1)+(6*5)+(5*0)+(4*5)+(3*4)+(2*8)+(1*7)=125
125 % 10 = 5
So 1315054-87-5 is a valid CAS Registry Number.
1315054-87-5Relevant articles and documents
Annular chiral amino compound containing carbamide group and amplifiable processes and application thereof
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Paragraph 0110-0112, (2017/08/29)
An annular chiral amino compound containing carbamide group is used as a pharmaceutical intermediate to prepare various annular chiral amide compounds. An amplifiable process for preparing the annular chiral amino compound containing carbamide group comprises: allowing alkamine hydrochloride to react with substituted carbamoyl and the like under alkaline conditions to obtain an annular alcoholic compound with carbamide group, allowing the annular alcoholic compound to react with sulfonyl chloride in the presence of an acid-binding agent to obtain an activated sulfonate compound, allowing the activated sulfonate compound to react with ammonia or sodium azide or hexamethyl-silicon ammonium salt to obtain an annular amino compound with carbamide group, allowing the annular amino compound with carbamide group to react with Boc2O to obtain the Boc-protected annular amino compound with carbamide group. The process provided herein uses cheap and easily-accessed raw and auxiliary materials, the process route has good atom economy, the reaction is simple, reaction conditions are mild, the process is easy to control, post-processing is simple, the yield is high, and the annular chiral amino compound is easy to produce in amplified manner.
