13152-96-0

Basic information

• Product Name: Methanone, (2,5-dimethylphenyl)(4-methylphenyl)-
• CAS NO: 13152-96-0
• Molecular Formula: C16H16O
• Molecular Weight: 224.302
• Mol File: 13152-96-0.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Methanone, (2,5-dimethylphenyl)(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (2,5-dimethylphenyl)(4-methylphenyl)-(13152-96-0)
• EPA Substance Registry System: Methanone, (2,5-dimethylphenyl)(4-methylphenyl)-(13152-96-0)

Safety Data

• Hazardous Substances Data: 13152-96-0(Hazardous Substances Data)

Upstream product

• 106-42-3 para-xylene 
• 13756-42-8 tert-butyl 4-methylbenzoate 
• 201230-82-2 carbon monoxide 
• 624-31-7 4-tolyl iodide 
• 19226-36-9 3-phenyl-5H-1,4,2-dioxazol-5-one 
• 104-82-5 4-Methylbenzyl chloride 
• 20809-75-0 Methyl-2-(2,5-dimethyl-phenyl)-2-hydroxy-3-oxo-succinat 
• 20809-77-2 Methyl-2,2-(2,5,4'-trimethyl-diphenyl)-3-oxo-succinat 
• 99-94-5 p-Toluic acid 
• 22328-43-4 2,5-dimethylbenzoyl chloride 
• 108-88-3 toluene 
• 721-45-9 1,4-dimethyl-2-(4-methylbenzyl)benzene 
• 874-60-2 4-methyl-benzoyl chloride 
• 95-72-7 2-chloro-1,4-dimethyl-benzene 

Downstream Products

• 721-45-9 1,4-dimethyl-2-(4-methylbenzyl)benzene 
• 613-26-3 2,6-dimethylanthracene 
• 146780-99-6 2,6-dimethyl-anthrone 
• 186971-82-4 9,10-dihydro-anthracene-2,6-dicarboxylic acid 
• 138308-89-1 2,6-anthracene dicarboxylic acid 
• 53039-57-9 (4-methoxyphenyl)-(2-methoxy-5-methylphenyl)methane 

Relevant articles and documents

Controlled photo-flow oxidative reaction (UV-FOR) platform for ultra-fast phthalide and API synthesis

An integrated photo-flow oxidative reaction (UV-FOR) platform approach is presented for the synthesis of phthalides. The current protocol is catalyst-free, and uses economical and abundant hydro-carbons and hydrocarbon derivatives such as benzoic acid, benzene, and xylene, as starting materials. The reaction is performed using oxygen as a green oxidant in a time- and labour-efficient manner. This integrated approach has been shown to be successful in making a UV-FOR platform suitable for the on-demand synthesis of phthalides and their further syntheses to 2-arylmethylbenzoic acids and arylogous Michael addition products under relatively mild conditions. The current protocol was further extended to the gram scale synthesis of an ischemic stroke-relevant active pharmaceutical ingredient (API), 3-N-butylphthalide (NBP), in a continuous flow process.

Co(III)-Catalyzed Synthesis of Quinazolines via C-H Activation of N-Sulfinylimines and Benzimidates

C-H activation of arenes has been established as an important strategy for heterocycle synthesis via annulations between arenes and unsaturated coupling partners. However, nitriles failed to act as such a coupling partner. Dioxazolones have been employed as a synthon of nitriles, and subsequent coupling with arenes such as N-sulfinylimines and benzimidates bearing a functionalizable directing group provided facile access to two classes of quinazolines under Co(III)-catalysis.

Design, synthesis and characterization of self-assembled As 2L3 and Sb2L3 cryptands

The syntheses and X-ray crystal structures of six new self-assembled supramolecular As and Sb-containing cryptands are described. Analysis in the context of previously reported As2L3 and Sb 2L3 cryptands reveals that small differences in ligand geometries result in significant differences in the helicity of the complexes and the stereochemistry of the metal coordination within the assembled complexes. Additionally, a new synthetic route is described which involves exposure of reactants to vacuum to help facilitate self-assembly.