131662-01-6Relevant articles and documents
Studies on 5-lipoxygenase inhibitors. I. Synthesis and 5-lipoxygenase- inhibitory activity of novel hydroxamic acid derivatives
Yatabe, Takumi,Kawai, Yoshio,Oku, Teruo,Tanaka, Hirokazu
, p. 966 - 972 (2007/10/03)
A series of novel hydroxamates has been prepared and tested for inhibitory activity towards rat polymorphonuclear leukocyte (PMN) 5- lipoxygenase (5-LO) in vitro and towards neutrophil migration in the rat air pouch model of inflammation in vivo. Many 3,4