1318072-81-9

Basic information

• Product Name: 4-methyl-N-(2-(1-methyl-1H-indol-3-yl)ethyl)benzenesulfonamide
• Synonyms: 4-methyl-N-(2-(1-methyl-1H-indol-3-yl)ethyl)benzenesulfonamide
• CAS NO: 1318072-81-9
• Molecular Weight: 328.435
• Mol File: 1318072-81-9.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 4-methyl-N-(2-(1-methyl-1H-indol-3-yl)ethyl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-N-(2-(1-methyl-1H-indol-3-yl)ethyl)benzenesulfonamide(1318072-81-9)
• EPA Substance Registry System: 4-methyl-N-(2-(1-methyl-1H-indol-3-yl)ethyl)benzenesulfonamide(1318072-81-9)

Safety Data

• Hazardous Substances Data: 1318072-81-9(Hazardous Substances Data)

Upstream product

• 61-54-1 tryptamine 
• 103549-24-2 tert-butyl [2-(1H-indol-3-yl)ethyl]carbamate 
• 919787-22-7 tert-butyl [2-(1-methyl-1H-indol-3-yl)ethyl]carbamate 
• 98-59-9 p-toluenesulfonyl chloride 
• 7518-21-0 2-(1-methyl-1H-indol-3-yl)ethylamine 
• 86658-78-8 N-tosyl tryptamine 
• 74-88-4 methyl iodide 
• 70-55-3 toluene-4-sulfonamide 
• 1912-48-7 2-(1-methyl-1H-indol-3-yl)acetic acid 
• 1334298-73-5 2-(1-methyl-1H-indol-3-yl)-N-tosylacetamide 

Downstream Products

• 1318072-94-4 C₂₈H₃₈N₂O₃SSi 
• 1356938-37-8 1,2,3,3a,8,8a-hexahydro-3a-(1,2,3,3a,8,8a-hexahydro-8-methyl-1-tosylpyrrolo[2,3-b]indol-3a-yl)-8-methyl-1-tosylpyrrolo[2,3-b]indole 
• 1609064-59-6 C₄₄H₅₄N₂O₆S 

Relevant articles and documents

Gold-Catalyzed Oxidative Cyclization of Tryptamine Derived Enynamides: A Stereoselective Approach to Tetracyclic Spiroindolines

In this work, we describe a new gold-catalyzed oxidative cascade cyclization of conjugated enynamides. The reaction could be carried out under relatively mild condition. In presence of a cationic gold catalyst bearing an N-heterocyclic carbene ligand, enynamides derived from tryptamine react with pyridine N-oxide, leading to the formation of a variety of tetracyclic spiroindolines in a stereoselective manner. (Figure presented.).

Ligand-Controlled Regiodivergence for Catalytic Stereoselective Semireduction of Allenamides

Ligand-controlled regiodivergence has been developed for catalytic semireduction of allenamides with excellent chemo- and stereocontrol. This system also provides an example of catalytic regiodivergent semireduction of allenes for the first time. The divergence of the semireduction is enabled by ligand switch with the same palladium pre-catalyst under operationally simple and mild conditions. Monodentate ligand XPhos exclusively promotes selective 1,2-semireduction to afford allylic amides, while bidentate ligand BINAP completely switched the regioselectivity to 2,3-semireduction, producing (E)-enamide derivatives.

Preparation method of azepano[4,5-b]indole compound

The invention discloses a preparation method of an azepano[4,5-b]indole compound, which comprises the following steps: by taking tryptamine or a derivative thereof as an initial raw material, protecting an NH2 group of a side chain alkyl group, protecting