131844-00-3

Basic information

• Product Name: 2-benzyl-4-<2-<5-(dimethylaminomethyl)furfurylthio>-ethylamino>-2,3-dihydro-3-oxo-1,2,5-thiadiazole 1,1,-dioxide
• CAS NO: 131844-00-3
• Molecular Weight: 436.556
• Mol File: 131844-00-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-benzyl-4-<2-<5-(dimethylaminomethyl)furfurylthio>-ethylamino>-2,3-dihydro-3-oxo-1,2,5-thiadiazole 1,1,-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzyl-4-<2-<5-(dimethylaminomethyl)furfurylthio>-ethylamino>-2,3-dihydro-3-oxo-1,2,5-thiadiazole 1,1,-dioxide(131844-00-3)
• EPA Substance Registry System: 2-benzyl-4-<2-<5-(dimethylaminomethyl)furfurylthio>-ethylamino>-2,3-dihydro-3-oxo-1,2,5-thiadiazole 1,1,-dioxide(131844-00-3)

Safety Data

• Hazardous Substances Data: 131844-00-3(Hazardous Substances Data)

Upstream product

• 66356-53-4 5-{[(2-aminoethyl)thio]methyl}-N,N-dimethyl-2-furfurylamine 
• 106350-10-1 4-amino-2-benzyl-2,3-dihydro-3-oxo-1,2,5-thiadiazole 1,1-dioxide 

Relevant articles and documents

Potential histamine H2-receptor antagonists. Synthesis, conformational studies and activity of novel 3-oxo-1,2,5-thiadiazole 1,1-dioxide derivatives.

New histamine H2-receptor antagonists bearing a novel "urea equivalent", the 3-oxo-1,2,5-thiadiazole 1,1-dioxide ring, have been synthesized in a transamination reaction. Open chain derivatives have also been obtained. Theoretical conformational analysis of the compounds has been carried out using a molecular modelling program. Semiempirical CNDO/2 calculations have also been performed. The antisecretory and cytoprotective activities of the compounds have been evaluated.