131890-73-8

Basic information

• Product Name: 1-(2-hydroxy-2-phenylethyl)-3,5-diphenylpyrazole
• Synonyms: 1-(2-hydroxy-2-phenylethyl)-3,5-diphenylpyrazole
• CAS NO: 131890-73-8
• Molecular Formula: C₂₃H₂₀N₂O
• Molecular Weight: 340.42
• Mol File: 131890-73-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 546.3°Cat760mmHg
• Flash Point: 284.2°C
• Appearance: /
• Density: 1.12g/cm³
• Vapor Pressure: 9.11E-13mmHg at 25°C
• Refractive Index: 1.622
• CAS DataBase Reference: 1-(2-hydroxy-2-phenylethyl)-3,5-diphenylpyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-hydroxy-2-phenylethyl)-3,5-diphenylpyrazole(131890-73-8)
• EPA Substance Registry System: 1-(2-hydroxy-2-phenylethyl)-3,5-diphenylpyrazole(131890-73-8)

Safety Data

• Hazardous Substances Data: 131890-73-8(Hazardous Substances Data)

Usage

Description

1-(2-hydroxy-2-phenylethyl)-3,5-diphenylpyrazole, also known as HPEPDP, is a chemical compound belonging to the pyrazole family, characterized by a unique chemical structure featuring a five-membered ring with two nitrogen atoms and three carbon atoms. It is synthesized through a series of chemical reactions, including the condensation of 1-phenyl-2,3-dimethyl-3-pyrazolin-5-one with benzaldehyde and subsequent reduction of the resulting enaminone.

Uses

Used in Medicinal Chemistry:
1-(2-hydroxy-2-phenylethyl)-3,5-diphenylpyrazole is used as a pharmaceutical compound for its potential anti-inflammatory, analgesic, and neuroprotective properties. Its unique structure and properties make it a promising candidate for the development of new drugs in the medical field.
Used in Materials Science:
In the field of materials science, 1-(2-hydroxy-2-phenylethyl)-3,5-diphenylpyrazole is used as a component in the development of novel optical and electronic materials. Its specific characteristics contribute to the advancement of these technologies, potentially leading to improved performance and functionality in various applications.

InChI:InChI=1/C23H20N2O/c26-23(20-14-8-3-9-15-20)17-25-22(19-12-6-2-7-13-19)16-21(24-25)18-10-4-1-5-11-18/h1-16,23,26H,17H2

Upstream product

• 96-09-3 styrene oxide 
• 1145-01-3 3,5-Diphenylpyrazole 
• 120-46-7 1,3-diphenylpropanedione 
• 4397-11-9 2-hydrazino-1-phenylethanol 

Downstream Products

• 131890-85-2 4-{2-[2-(3,5-Diphenyl-pyrazol-1-yl)-1-phenyl-ethoxy]-ethyl}-morpholine 
• 131890-81-8 {2-[2-(3,5-Diphenyl-pyrazol-1-yl)-1-phenyl-ethoxy]-ethyl}-diethyl-amine 
• 131890-89-6 1-[2-(3,5-Diphenyl-pyrazol-1-yl)-1-phenyl-ethyl]-piperidine 
• 131890-88-5 3,5-Diphenyl-1-(2-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-pyrazole 
• 131890-91-0 1-[2-(3,5-Diphenyl-pyrazol-1-yl)-1-phenyl-ethyl]-4-methyl-piperazine 
• 131890-90-9 4-[2-(3,5-Diphenyl-pyrazol-1-yl)-1-phenyl-ethyl]-morpholine 
• 131890-87-4 [2-(3,5-Diphenyl-pyrazol-1-yl)-1-phenyl-ethyl]-diethyl-amine 
• 131890-86-3 N,N-dimethyl 1-(2-amino-2-phenylethyl)-3,5-diphenyl-1H-pyrazole 
• 144454-92-2 5-(3,5-Diphenyl-pyrazol-1-yl)-4-phenyl-pyrimidin-2-ylamine 
• 144455-08-3 2-{[5-(3,5-Diphenyl-pyrazol-1-yl)-4-phenyl-pyrimidin-2-yl]-methyl-amino}-1-(4-methyl-piperazin-1-yl)-ethanone 
• 144455-01-6 1-(2,6-Dimethyl-morpholin-4-yl)-2-[5-(3,5-diphenyl-pyrazol-1-yl)-4-phenyl-pyrimidin-2-ylamino]-ethanone 
• 144455-07-2 2-{[5-(3,5-Diphenyl-pyrazol-1-yl)-4-phenyl-pyrimidin-2-yl]-methyl-amino}-1-morpholin-4-yl-ethanone 
• 144455-00-5 2-[5-(3,5-Diphenyl-pyrazol-1-yl)-4-phenyl-pyrimidin-2-ylamino]-1-morpholin-4-yl-ethanone 
• 144455-04-9 2-{[5-(3,5-Diphenyl-pyrazol-1-yl)-4-phenyl-pyrimidin-2-yl]-methyl-amino}-N-(2-ethoxy-ethyl)-acetamide 

Relevant articles and documents

An efficient synthesis of β-hydroxyethylpyrazoles from propylene and styrene oxide using Cs2CO3

Bases such as caesium carbonate efficiently catalyze the regioselective ring opening of propylene and styrene oxide with various substituted pyrazoles.