1319721-62-4Relevant articles and documents
A practical synthesis of capped 4-methylumbelliferyl hyaluronan disaccharides and tetrasaccharides as potential hyaluronidase substrates
Gold, Henrik,Munneke, Stefan,Dinkelaar, Jasper,Overkleeft, Herman S.,Aerts, Johannes M.F.G.,Codée, Jeroen D.C.,Van Der Marel, Gijs A.
, p. 1467 - 1478 (2011/08/22)
The synthesis of hyaluronan dimers and tetramers equipped with a 4-methylumbelliferyl group at the reducing end to potentially allow monitoring of hyaluronidase activities is described. The 4-OH at the non-reducing glucuronate in the presented series is either removed or methylated to prohibit transglycosylase reactions, leading to a total of four probes.