1320256-74-3Relevant articles and documents
Enantioselective copper-catalyzed conjugate addition of trimethylaluminum to β,γ-unsaturated α-ketoamides: Efficient access to γ-methyl-substituted carbonyl compounds
Goncalves-Contal, Sylvie,Gremaud, Ludovic,Alexakis, Alexandre
, p. 12701 - 12704 (2013/12/04)
Picture perfect: By using the reagent trimethylaluminium and β,γ-unsaturated α-ketoamides, 1,4-adducts were obtained with perfect 1,4-regioselectivity and good to excellent yields and ee values. The potential synthetic utility of the methodology was highl