1320360-01-7Relevant articles and documents
A multicomponent coupling reaction induced by insertion of arynes into the C=O bond of formamide
Yoshioka, Eito,Kohtani, Shigeru,Miyabe, Hideto
, p. 6638 - 6642 (2011)
And aryne makes three: The three-component coupling of arynes, DMF, and active methylenes has provided an efficient method for the synthesis of 2H-chromene and coumarin derivatives (see scheme). The sequential multistep reactions are driven by the release of strain energy in the arynes and intermediates, and this finding was supported by thermodynamics. Copyright