132112-35-7 Usage
Description
Ropivacaine hydrochloride is a pure S(-)enantiomer with a propyl group on the piperidine nitrogen atom, structurally related to lidocaine and characterized as a potent and reversible blocker of sodium channels in nerve fibers. It is a white solid that has been used as a local anesthetic in various medical applications.
Uses
Used in Anesthetic Applications:
Ropivacaine hydrochloride is used as a local anesthetic for surgical procedures and childbirth, providing effective pain relief and reducing the need for more invasive anesthetic techniques.
Used in Pharmaceutical Industry:
Ropivacaine hydrochloride is used as an analyte in tandem mass spectrometry to test its effect on breast cancer cell methylation, potentially contributing to the development of new cancer treatments.
Used in Medical Research:
Ropivacaine hydrochloride is used as a research tool to study the mechanisms of action and effects of local anesthetics on various physiological processes, including myocardial contractile force and nerve fiber function.
Biochem/physiol Actions
Local anaesthetic with less cardiotoxicity than bupivacaine; causes reversible blockade of impulse propagation along nerve fibres by preventing the inward movement of sodium ions through the cell membrane of the nerve fibers.
Check Digit Verification of cas no
The CAS Registry Mumber 132112-35-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,1,1 and 2 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 132112-35:
(8*1)+(7*3)+(6*2)+(5*1)+(4*1)+(3*2)+(2*3)+(1*5)=67
67 % 10 = 7
So 132112-35-7 is a valid CAS Registry Number.
InChI:InChI=1/C17H26N2O.ClH.H2O/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3;;/h7-9,15H,4-6,10-12H2,1-3H3,(H,18,20);1H;1H2
132112-35-7Relevant articles and documents
Process of making optically pure L-pipecolic acid and process of making anesthetics and intermediates therefrom
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Page/Page column 5, (2008/06/13)
The present invention describes a novel process of preparation of optically pure L-Pipecolic acid and an improved process for the conversion of L-pipecolic acid to L-N-(2,6-dimethylphenyl)-1-propyl-2-piperidinocarboxamide, its hydrochloride salt and hydrochloride monohydrate.